Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies

Xiao, Amy; Tan, Marianne L.; Wu, Landy M.; Asrani, Varsha M.; Windsor, John A.; Yadav, Dhiraj; Petrov, Maxim S.

doi:10.1016/s2468-1253(16)30004-8

Cited by 532 publications

(421 citation statements)

References 68 publications

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“…The annual incidence of AP ranges from 13 to 45 cases per 100,000 population with the global estimate of 33.74 cases per 100,000 population, causing uneven burden across the globe. The health-care cost in the United States is reported to be $2.5 billion (1, 4, 5). Gallstones and alcoholism are the long-established two most common etiological factors, and other risk factors such as genetic predisposition, drugs, smoking, type 2 diabetes, and endoscopic retrograde cholangiopancreatography play a part (1, 3, 6).…”

Section: Introductionmentioning

confidence: 99%

Recent Advances on Nutrition in Treatment of Acute Pancreatitis

Pan

Shamoon

et al. 2017

Front. Immunol.

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Acute pancreatitis (AP) is a common abdominal acute inflammatory disorder and the leading cause of hospital admission for gastrointestinal disorders in many countries. Clinical manifestations of AP vary from self-limiting local inflammation to devastating systemic pathological conditions causing significant morbidity and mortality. To date, despite extensive efforts in translating promising experimental therapeutic targets in clinical trials, disease-specific effective remedy remains obscure, and supportive care has still been the primary treatment for this disease. Emerging evidence, in light of the current state of pathophysiology of AP, has highlighted that strategic initiation of nutrition with appropriate nutrient supplementation are key to limit local inflammation and to prevent or manage AP-associated complications. The current review focuses on recent advances on nutritional interventions including enteral versus parenteral nutrition strategies, and nutritional supplements such as probiotics, glutamine, omega-3 fatty acids, and vitamins in clinical AP, hoping to advance current knowledge and practice related to nutrition and nutritional supplements in clinical management of AP.

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Section: Introductionmentioning

confidence: 99%

Recent Advances on Nutrition in Treatment of Acute Pancreatitis

Pan

Shamoon

et al. 2017

Front. Immunol.

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“…Studies from other part of the world would greatly enrich the knowledge on these relationships and should be viewed favorably by funding agencies [4,10]. …”

Section: Present Challenges and Future Directionsmentioning

confidence: 99%

“…An estimated 426,000 persons were newly diagnosed with pancreatic cancer globally in year 2015 alone [3]. The worldwide incidence of pancreatic cancer in the general population is estimated at 8.1 per 100,000 person-years [4], and is significantly higher among men than women (Figure 1). Further, pancreatic cancer incidence is significantly higher in North America than the rest of the world [4].…”

Section: Introductionmentioning

confidence: 99%

“…The worldwide incidence of pancreatic cancer in the general population is estimated at 8.1 per 100,000 person-years [4], and is significantly higher among men than women (Figure 1). Further, pancreatic cancer incidence is significantly higher in North America than the rest of the world [4]. Given that early detection of pancreatic cancer in the general population is virtually impossible and taking into account the absence of effective therapies, prevention is currently the only way to meaningfully reduce the burden of this disease.…”

Section: Introductionmentioning

confidence: 99%

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Tobacco and alcohol as risk factors for pancreatic cancer

Korc

Jeon

Edderkaoui

et al. 2017

Best Practice & Research Clinical Gastroenterology

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Pancreatic cancer is projected to become the leading cause of cancer deaths by 2050. The risk for pancreatic cancer may be reduced by up to 27% by modifying lifestyle risk factors, most notably tobacco smoking. Based on analysis of more than 2 million unselected individuals from general population, this article quantified the risk of pancreatic cancer in relation to lifelong tobacco smoking and alcohol consumption status, both alone and in combination. It also provided a state-of-the-art review of animal studies on the effect of tobacco smoke and alcohol on genetically engineered mouse models of pancreatic precursor lesions, as well as the role of pancreatic stellate cells and immune cells in pancreatic carcinogenesis activated by tobacco and alcohol.

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“…With global incidence of 34 per 100,000 [1,2], acute pancreatitis is one of the most frequent gastrointestinal diseases but clinical research on gastrointestinal motility in its setting remained, until very recently, nescient. While gastrointestinal barrier function in acute pancreatitis has been investigated in dozens of prospective clinical studies since 1980s [3], very little is known about changes in gastrointestinal motility associated with this disease.…”

Section: Editorialmentioning

confidence: 99%

The nescience and nascence of gastrointestinal motility research in acute pancreatitis

Petrov

2017

Scandinavian Journal of Gastroenterology

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Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies

Cited by 532 publications

References 68 publications

Recent Advances on Nutrition in Treatment of Acute Pancreatitis

Recent Advances on Nutrition in Treatment of Acute Pancreatitis

Tobacco and alcohol as risk factors for pancreatic cancer

The nescience and nascence of gastrointestinal motility research in acute pancreatitis

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