Global Cosmetic Regulations? A Long Way To Go …

Schneider, Sandra B.

doi:10.1016/b978-0-8155-1569-2.50016-6

Cited by 6 publications

(2 citation statements)

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“…Organic UV filters are divided into UVA, UVB or broad‐spectrum absorbers, which depend on the chemical structure of the molecule, e.g. p‐methylbenzoates, cinnamates, salicylates, benzophenones, anthranilates, dibenzoylmethanes, camphor derivatives, and other many classes of molecules . Sunscreens must be photostable when irradiated with sunlight since the aim of the photoprotective product is to ensure a constant efficacy during the exposure period .…”

Section: Introductionmentioning

confidence: 99%

Development of a photoprotective and antioxidant nanoemulsion containing chitosan as an agent for improving skin retention

Cerqueira-Coutinho

Santos-Oliveira

Santos

et al. 2015

Engineering in Life Sciences

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Sunscreens are destined to topical application and should protect skin against ultraviolet radiation; furthermore, they are toxic substances and should not reach the bloodstream, so they must be retained in the skin. In the present work, an oil-inwater photoprotective and antioxidant nanoemulsion (NE) containing chitosan was developed. Preliminary studies were performed aiming to choose the surfactant to be used in this NE; stability of the formulas was determined by dynamic light scattering after their preparation and after 7 days. A blend of surfactants, polyoxyethylene sorbitan monooleate, and sorbitan monooleate was selected for the preparation of the NE, as well as the following organic sunscreens: benzophenone-3, diethylamino hydroxybenzoyl hexylbenzoate, octocrylene and octylmethoxycinnamate, and also pomegranate antioxidant extract and chitosan. The antioxidant extract with the highest antioxidant activity was chosen based on a screening of plant extracts by DPPH• (2,2-diphenyl-1-picrylhydrazyl) assay. Photostability of the sunscreens and in vitro efficacy and safety of the formulations were also evaluated. Results showed that the developed photoprotective and antioxidant NE containing chitosan was stable for at least 6 months, photostable when irradiated in a solar simulator, and effective. Additionally, chitosan acted by promoting retention of the formulation in epidermis, thus increasing formulation safety.

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Section: Introductionmentioning

confidence: 99%

Development of a photoprotective and antioxidant nanoemulsion containing chitosan as an agent for improving skin retention

Cerqueira-Coutinho

Santos-Oliveira

Santos

et al. 2015

Engineering in Life Sciences

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“…The organic UV filters are broadly divided into UVA , UVB or broad spectrum absorbers active ingredients in sunscreens, as well as the permitted maximum concentrations, differ considerably worldwide [3].In this study, we have concentrated on Diethylamino hydyoxybenzoyl hexyl benzoate(Uvinul ® A Plus) and Ethylhexyl triazone (Uvinul ® T 150) .Organic filters possess commercial interest because of the many cinnamates being currently used as organic sunscreen [4]. Most of them like Uvinul ® T 150 absorb well in the UVB region (290-320 nm) and some like Uvinul ® A Plus can extend into the UVA(320-400 nm).…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Broad-Spectrum Sunscreens Loaded Nanostructured Lipid Carrier

Chen¹,

Xia²

2013

AMR

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A comprehensive photoprotective formulation was developed to enhance photoprotection ,compared to a conventional nanoemulsion ,having the concentration of two new molecular sunscreens, namely Diethylamino hydyoxybenzoyl hexyl benzoate(Uvinul ® A Plus) and Ethylhexyl triazone(Uvinul® T 150). In the present paper, the sunscreen mixture was incorporated into nanostructured lipid carriers (NLCs). After the production by hot high pressure homogenization, the NLC were analyzed in terms of particle size, physical state, particle shape, ultraviolet absorbance and stability. The particle size for all NLC was around 100-900 nm after production. The determination of 2 organic UV filters was performed by HPLC with UV spectrophotometric detection. The loading capacities for molecular sunscreens was up to 30%. In the sunlight, the retention rate of Uvinul ® A Plus and Uvinul ® T150 was still up to 80% after three months .

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