Glioblastoma multiforme: radiologic-pathologic correlation.

Rees, John H.; Smirniotopoulos, James G.; Jones, Robert; Wong, Karen

doi:10.1148/radiographics.16.6.8946545

Cited by 158 publications

(193 citation statements)

References 0 publications

Supporting

Mentioning

162

Contrasting

Unclassified

Order By: Relevance

“…9,14 Among the tumor types studied, PCLs usually have the highest cellularity, followed by glioblastomas and brain metastases. [28][29][30] Elevated FA from the ER of glioblastomas in comparison with both brain metastases and PCLs in our study indicates that diffusion anisotropy may not directly correlate with tumor cellularity. It has been reported that anisotropy in tumor tissue is affected by several factors including extracellularto-intracellular space ratio, extracellular matrix, tortuosity, and vascularity.…”

Section: Adc and Fa From The Enhancing Region Of The Tumormentioning

confidence: 97%

Differentiation between Glioblastomas, Solitary Brain Metastases, and Primary Cerebral Lymphomas Using Diffusion Tensor and Dynamic Susceptibility Contrast-Enhanced MR Imaging

Wang

Kim²,

Chawla³

et al. 2011

AJNR Am J Neuroradiol

167

149

View full text Add to dashboard Cite

show abstract

Section: Adc and Fa From The Enhancing Region Of The Tumormentioning

confidence: 97%

Differentiation between Glioblastomas, Solitary Brain Metastases, and Primary Cerebral Lymphomas Using Diffusion Tensor and Dynamic Susceptibility Contrast-Enhanced MR Imaging

Wang

Kim²,

Chawla³

et al. 2011

AJNR Am J Neuroradiol

167

149

View full text Add to dashboard Cite

show abstract

“…The most common MR findings of GBM are a heterogeneous mass in the white matter with vasogenic edema, thick irregularly enhancing walls and necrosis. While cystic appearance with associated thin round walls has been reported in GBM, this finding is unusual (9). Occasionally, the cystic mass will harbor a mural nodule of enhancement.…”

Section: Discussionmentioning

confidence: 79%

“…Both of these features are found in glioblastomas (9). The most common MR findings of GBM are a heterogeneous mass in the white matter with vasogenic edema, thick irregularly enhancing walls and necrosis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Unusual magnetic resonance imaging appearance of multiple cystic lesions in glioblastoma multiforme

Lyons

2011

Turkish Neurosurgery

View full text Add to dashboard Cite

The differential diagnosis of multiple ring-enhancing intraaxial lesions includes neoplastic, infectious, inflammatory, demyelinating and vascular lesions. We report a case of a 41-year-old man who presented with a brief history of left lower extremity weakness and sensory loss. Magnetic resonance imaging demonstrated multiple ring-enhancing lesions in the right frontal and parietal lobes. Neuroradiology interpretation was felt to be unlikely for a neoplastic process. The patient underwent stereotactic brain biopsy, which was diagnostic for glioblastoma multiforme. This case demonstrates the importance of histological confirmation of intraaxial brain lesions whenever feasible. The course of his disease and treatment are discussed and the literature reviewed. KeywOrds: Glioblastoma multiforme, Ring-enhancing, Brain biopsy, Magnetic resonance imaging ÖZÇok sayıda halka şeklinde kontrast tutan intraaksiyal lezyonların ayırıcı tanısı arasında neoplastik, enfeksiyöz, enflamatuvar, demiyelinizan ve vasküler lezyonlar vardır. Kısa bir sol alt ekstremite zayıflığı ve duyu kaybı öyküsüyle başvuran 41 yaşında bir erkeği sunuyoruz. Manyetik rezonans görüntüleme sağ frontal ve parietal loblarda çok sayıda halka şeklinde kontrast tutan lezyon gösterdi. Nöroradyolojinin yorumu neoplastik bir süreç olmasının pek olası olmadığı şeklindeydi. Hastaya stereotaktik beyin biyopsisi yapıldı ve glioblastoma multiforme tanısı kondu. Bu vaka mümkün olduğunda intraaksiyal beyin lezyonlarının histolojik olarak doğrulanmasının önemini göstermektedir. Hastalığın seyri ve tedavi anlatılmakta ve literatür gözden geçirilmektedir.

show abstract

“…It is found most commonly as a primary tumor, with secondary tumor characteristics as result of transformation from low-grade glioma. [1][2][3][4][5][6][7][8] Intraventricular tumors represent only 10% of central nervous system neoplasms. Of those, the reported malignancy rate is 13% of all cases.…”

Section: Introductionmentioning

confidence: 99%

Third Ventricular Glioblastoma Multiforme: Case Report and Literature Review

Hariri¹,

Farr²,

Corsino³

et al. 2014

J Neurol Surg B

View full text Add to dashboard Cite

BackgroundGBM is an intra-axial mass, localized to the frontotemporal region that accounts for 50 to 60% of astrocytomas and 12 to 15% of intracranial tumors. It is found most commonly as a primary tumor, with secondary tumor characteristics as result of transformation from low-grade glioma. 1-8 Intraventricular tumors represent only 10% of central nervous system neoplasms. Of those, the reported malignancy rate is 13% of all cases. Lee and Manzano enumerated the most frequently found ventricular system tumors, presented in ►Table 1. 9 The rarest lesions of the intraventricular region are GBM, ependymomas, gangliocytomas, and gliosarcomas. 10 Ependymomas occur at a frequency of 0.25% 11 and gangliocytomas with a frequency of 0.1 to 0.5%. 12 When AbstractBackground Glioblastoma multiforme (GBM) typically presents in the supratentorial white matter, commonly within the centrum semiovale as a ring-enhancing lesion with areas of necrosis. An atypical presentation of this lesion, both anatomically as well as radiographically, is significant and must be part of the differential for a neoplasm in this anatomical location. Case Description We present a case of a 62-year-old woman with headaches, increasing somnolence, and cognitive decline for several weeks. Magnetic resonance imaging demonstrated mild left ventricular dilatation with a well-marginated, homogeneous, and nonhemorrhagic lesion located at the ceiling of the third ventricle within the junction of the septum pellucidum and fornix, without exhibiting the typical radiographic features of hemorrhage or necrosis. Final pathology reports confirmed the diagnosis of GBM. Conclusion This case report describes an unusual location for the most common primary brain neoplasm. Moreover, this case identifies the origin of a GBM related to the paracentral ventricular structures infiltrating the body of the fornix and leaves of the septum pellucidum. To our knowledge this report is the first reported case of a GBM found in this anatomical location with an entirely atypical radiographic presentation.

show abstract

Glioblastoma multiforme: radiologic-pathologic correlation.

Cited by 158 publications

References 0 publications

Differentiation between Glioblastomas, Solitary Brain Metastases, and Primary Cerebral Lymphomas Using Diffusion Tensor and Dynamic Susceptibility Contrast-Enhanced MR Imaging

Differentiation between Glioblastomas, Solitary Brain Metastases, and Primary Cerebral Lymphomas Using Diffusion Tensor and Dynamic Susceptibility Contrast-Enhanced MR Imaging

Unusual magnetic resonance imaging appearance of multiple cystic lesions in glioblastoma multiforme

Third Ventricular Glioblastoma Multiforme: Case Report and Literature Review

Contact Info

Product

Resources

About