Glibenclamide and Tolbutamide in Human Serum: Rapid Measurement of the Free Fraction

Determination of glibenclamide in human plasma by liquid chromatography and atmospheric pressure chemical ionization/MS-MS detection

“…Most of them are based on the reversed-phase separation mechanism with C18 [3][4][5][6][7][8][9][10][11][12][13], or C8 stationary phases [14,15]. Normal-phase separation mechanism using silica stationary phase was also mentioned [16].…”