Glaucoma drainage devices; past, present, and future

Lloyd, Andrew W.; Lim, Kin Sheng; Allan, Bruce; Lloyd, Andrew W.; Muir, A L; Khaw, PT

doi:10.1136/bjo.82.9.1083

Cited by 169 publications

(126 citation statements)

References 61 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…The use of glaucoma drainage devices (GDDs) as a filtering procedure was first reported in 1907 [3]. They are generally used for the treatment of complicated cases after the failure of other surgical approaches [15].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

Bissig

Feusier²,

Mermoud³

et al. 2010

Int Ophthalmol

View full text Add to dashboard Cite

The efficacy and safety of a newly designed Ex-PRESS X-200 drainage device for the surgical treatment of glaucoma was evaluated. A clinical, prospective, monocentric, non-randomised, unmasked study on patients with medically uncontrolled glaucoma was performed. A superficial scleral flap was created. A posterior deep sclerectomy (DS) was dissected without opening the Schlemm's canal and an Ex-PRESS X-200 device was inserted under the scleral flap into the anterior chamber to drain aqueous humour into the intrascleral space. Biomicroscopy, best-corrected visual acuity (BCVA), applanation intra-ocular pressure (IOP) measurements, and fundus examination were performed before surgery, on the first day, the first week, and 1, 2, 3, 6, 12 and 18 months after surgery. The mean follow-up was 18.6 ± 2.4 months (mean ± SD) for the 26 eyes that were treated with the Ex-PRESS X-200 device. Preoperatively, the mean BCVA was 0.6 ± 0.3, the mean IOP was 22.0 ± 5.1 mmHg, and the mean number of medications per patients was 2.8 ± 0.8. Eighteen months after surgery the mean BCVA was 0.5 ± 0.4, the mean IOP was reduced to 12.0 ± 3.9 mmHg, and the mean number of medications per patient was 0.6 ± 1.2. Eighty-five percent of patients achieved an IOP \ 18 mmHg with or without medication and 69% without medication. Post-operative complications were hyphaema (15%), Seidel (15%), encysted blebs (54%) and bleb fibrosis in 8% of patients. Mitomycin C(MMC) was administered to 15 patients (58%) with needling being performed on 10 (38%) of these patients. Mid-term results of DS with the Ex-PRESS X-200 implant demonstrated its efficacy in controlling IOP with few post-operative complications in difficult eyes with an increased risk of surgery failure.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Trabeculectomy, first introduced in 1968, is a widely-used penetrating filtration surgery (PFS) [2,3]. While it is effective in controlling intra-ocular pressure (IOP) [2,4,5], trabeculectomy can lead to potentially sight-threatening complications [6,7].…”

Section: Introductionmentioning

confidence: 99%

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

Bissig

Feusier²,

Mermoud³

et al. 2010

Int Ophthalmol

View full text Add to dashboard Cite

show abstract

“…A tube connects the anterior chamber to a plate located in the conjunctival Tenon's space at the level of the equator between the extraocular muscles. The most common and reported complications include: athalamia, postsurgical hypotony, contact of the tube with the cornea, contact of the tube with the iris or lens, choroidal hemorrhage, hyphema, and for its location and size, changes in the palpebral motility and diplopia 1 . Some authors have reported a hypotonic phase of one week followed by a hypertensive phase (reported in Ahmed, Arq Bras Oftalmol.…”

Section: Discussionmentioning

confidence: 99%

“…Molteno (2) with one or two plates The bestis the most known of these is the Molteno (2) with one or two plates, but there are also other models such as the Krupin (3,4) , the Baerveldt (5) and the Ahmed (6) . All these implants, which can lead to surgical complications (1) , are designed to drain the aqueous humor from the anterior chamber towards the conjunctival sub-Tenon's space, forming a filtering bleb around the plate at the height of the eye's equator. The differences are the surface drainage area of the devices and the presence or absence of a valve mechanism.…”

Section: Introductionmentioning

confidence: 99%

“…For intraocular pressure (IOP) control in patients with refractory glaucoma, special devices called filter implants are used for glaucoma surgery (1) . Molteno (2) with one or two plates The bestis the most known of these is the Molteno (2) with one or two plates, but there are also other models such as the Krupin (3,4) , the Baerveldt (5) and the Ahmed (6) .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Microdevice for aqueous humor drainage Maldonado Bas - Pförtner

Maldonado-Bas¹,

Maldonado-Junyent²,

Maldonado-Junyent³

2011

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

RESUMEN Methods:In a prospective study, following the protocol, 16 eyes with refractory glaucoma were included and operated. Intraocular pressure ≤21mmHg with or without additional medication was considered successful. The follow-up was one year. Averages, percentages and their 95% confidence bands were calculated. Analysis of variance for repeated measures was used to compare averages. Results: The average preoperative intraocular pressure was 32.81 mmHg, SD ± 10.94 mmHg in a range of 14 to 50 mmHg. The average post-surgical intraocular pressure at one year was 12.43 mmHg, SD ± 2.85 mmHg in a range of 7 to 19 mmHg. The difference between the pre-and post-surgery average intraocular pressure was 20.38 mmHg. The number of successes was 14 eyes (87.5%, confidence interval (CI) 95% 61.6% -98.6%). The number of failures was two eyes (12.5%, CI 95% 1.43% -38.4%). Conclusions:The results show that the microdevice is successful for the treatment of refractory glaucoma.

show abstract