Glaucoma and Peters' anomaly

Heath, Dominic; Shields, M. Bruce

doi:10.1007/bf00167884

Cited by 7 publications

(10 citation statements)

References 3 publications

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“…Approximately half of patients with Peters anomaly develop glaucoma, and glaucoma secondary to Peters anomaly is an important complication that can affect visual prognosis [6,7,10]. In this study, VA was significantly poorer for the eyes with glaucoma than for those without glaucoma.…”

Section: Discussionmentioning

confidence: 50%

“…However, there were cases in which TLO was difficult to perform. Kupfer and Heath [7,9] revealed that the structures of the anterior chamber angle were grossly normal, aside from evidence of premature aging based on abundant broad-banded collagen fibers in the trabecular lamellae. However, Shields noted that a high insertion of the anterior uvea into the trabecular meshwork is a common finding in some cases of secondary childhood glaucoma [20].…”

Section: Discussionmentioning

confidence: 99%

“…Systemic involvement may present as head anomalies, facial dysmorphism, and ear abnormalities [2]. Approximately half the patients with Peters anomaly have concurrent glaucoma [6,7]. The mechanism of the glaucoma secondary to Peters anomaly is only partially understood.…”

Section: Introductionmentioning

confidence: 99%

“…The mechanism of the glaucoma secondary to Peters anomaly is only partially understood. The pathogenesis of glaucoma secondary to Peters anomaly is thought to result from trabeculodysgenesis or angle closure mechanisms associated with iridocorneal and lenticulocorneal adhesions [7]. In the series of Townsend et al, five of the fourteen patients with Peters anomaly had glaucoma, and all showed peripheral anterior synechiae except one with aniridia [8].…”

Section: Introductionmentioning

confidence: 99%

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Risk and Prognostic Factors for Glaucoma Associated with Peters Anomaly

Yokota,

Hirooka,

Okada

et al. 2023

JCM

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Glaucoma secondary to Peters anomaly is an important factor affecting visual prognosis, but there are few reports on the condition. This study aimed to investigate the characteristics of glaucoma associated with Peters anomaly and glaucoma surgery outcomes. This retrospective study included 31 eyes of 20 patients with Peters anomaly. Peters anomaly was classified into three stages: Stage 1, with a posterior corneal defect only; Stage 2, a corneal defect with iridocorneal adhesion; and Stage 3, a corneal defect with lens abnormalities. The associations between glaucoma and anterior segment dysgenesis severity, visual prognosis, and glaucoma surgery outcomes were analyzed. Sixteen eyes of ten patients developed glaucoma. Stage 1 Peters anomaly had no glaucoma, 52% of Stage 2 had glaucoma, and 75% of Stage 3 had glaucoma. Of the 16 eyes with glaucoma, 11 underwent surgery. Eight of these eleven eyes achieved intraocular pressure (IOP) control. Five of the nine eyes that underwent trabeculotomy (TLO) succeeded, and none had corneal staphyloma. Three of the four eyes for which TLO was ineffective had corneal staphyloma (p = 0.0331). Patients with Peters anomaly are more likely to develop glaucoma as anterior segment dysgenesis progresses, and the effect of TLO is limited if corneal staphyloma is present.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Risk and Prognostic Factors for Glaucoma Associated with Peters Anomaly

Yokota,

Hirooka,

Okada

et al. 2023

JCM

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“…Sensory deprivation, amblyopia, and glaucoma are significant sequelae of Peters’ anomaly. 8 It is vital for the ophthalmologist to classify it as either Type 1 or Type 2, and to receive multiple consultations from neonatology and genetics pending a diagnosis following birth. 9,10 A later diagnosis recommends that patients undergo molecular genetic testing and receive consults from retina, cornea, and glaucoma specialists.…”

Section: Short Reportmentioning

confidence: 99%

Peters’ Anomaly

Sault

Sheridan

2013

Ophthalmol Eye Dis

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Pupillary block in Peters’ anomaly

et al. 2008

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Peters' anomaly is a congenital disorder characterized by central corneal opacity and iris adhesions that extend to the periphery of the corneal opacity. The depth of the anterior chamber (AC) varies among affected individuals. Even if the AC is shallow, however, the angle usually remains open. As far as we are aware, no cases have been reported in which an AC has not formed. We present a rare case of Peters' anomaly with pupillary block leading to a fl attened AC. Case ReportThe patient was a 2-month-old boy who was delivered spontaneously at 39 weeks of gestation with a birth weight of 2650 g. There was no family history of ophthalmologic problems other than refractive errors. Corneal opacity was present in the patient's right eye at birth. The synechiae extended from the central iris to the periphery of the corneal opacity, and the AC appeared extremely shallow under microscope examination. The corneal diameter was 11.5 mm (horizontal) × 11.0 mm (vertical) OD and 10.5 mm × 10.5 mm OS. The cornea was not bulging forward. No abnormalities of lens, vitreous cavity, or retina were detected by ultrasonography in the B-scan mode. No clinical abnormalities were observed in the left eye. Intraocular pressure was 31 mmHg OD and 10 mmHg OS. We made a diagnosis of unilateral Peters' anomaly. Ultrasound biomicroscopy revealed the absence of an AC in the right eye (Fig. 1). The fi ndings of the lens surface were uncertain. To reduce the intraocular pressure in the right eye, we attempted to perform trabeculotomy under general anesthesia. We fi rst LETTERS

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Glaucoma and Peters' anomaly

Cited by 7 publications

References 3 publications

Risk and Prognostic Factors for Glaucoma Associated with Peters Anomaly

Risk and Prognostic Factors for Glaucoma Associated with Peters Anomaly

Peters’ Anomaly

Pupillary block in Peters’ anomaly

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