“…These substructures are known to possess varying biological activities. The 2(5H)-furanone moiety occurs in many natural products that exhibit biological activities ranging from antibiotic (Miao andAndersen, 1991 andDavidson andIreland, 1990), cytotoxic (Ortega et al, 2000, Bohlmann et al, 1982aand Bohlmann et al, 1982b and antitumor properties (Hung et al, 1990) to inhibition of cholesterol biosynthesis (Kuhnt et al, 1990). On the other hand the dihydrofuran-4-one moiety is known for its antitumoral activity (Smith et al, 1981, Kupchan et al, 1976and LeQuesne et al, 1978.…”