Glass Ampoules: Risks and Benefits

Abstract

Team training and information provided by the pharmaceutical industry on the use of ampoules are fundamental in the prophylaxis of accidents and contaminations. The search for safer materials to replace glass is also important.

Applying Theory to Understand and Modify Nurse Intention to Adhere to Recommendations regarding the Use of Filter Needles: An Intervention Mapping Approach

“…In fact, glass ampoules possess good chemical resistance; they are also impermeable and easy to clean and administer and can be sterilized and vacuumed. Moreover, glass ampoules allow for storage of photosensitive substances and the accurate measurement of medication [1]. However, the use of glass ampoules involves several risks, the most widely reported being the introduction of glass particles in medication [1–4].…”

“…Moreover, glass ampoules allow for storage of photosensitive substances and the accurate measurement of medication [1]. However, the use of glass ampoules involves several risks, the most widely reported being the introduction of glass particles in medication [1–4]. The introduction of particles in parenteral injections can lead to complications for patients [5–8].…”

Analysis of upper-limb movements to open glass ampoules and training methods in nursing education

“…AO may cause injuries to fingers and hands of the opener during neck breaking, dispersal of glass microparticles and contamination of ampoule contents. Finger and hand injuries can be painful for medical staff whilst also increasing the risk of secondary infections in patients when bacteria adhering to fingers and hands of medical staff are introduced into ampoule contents (Carraretto et al, 2011;Parker, 1995). Additionally, scattering of glass fragments poses a risk of organ damage in patients if these fragments enter the ampoule contents (Yamaoka et al, 1976;Katz et al, 1973;Pinnock, 1984;Carbone-Traber et al, 1986;Sabon et al, 1989;Giambrone, 1991).…”

Potential threat of meningitis from ampoule impurities: Prevention is always better than cure!

“…A small dot placed a few millimetres above the incision indicates the correct orientation for snapping the ampoule open. [ 1 ] In the ‘rupture disk’ system, an area of fragility is caused at the strangulation point using a temper process that partially penetrates the glass causing an area of fragility or weak point. A band is then painted at the strangulation point, indicating its point of weakness[ 1 ] [ Figure 1a ].…”

“…Use of filters in needles and use of smaller gauge needles have also been advocated as measures to reduce loading of glass micro particles in syringes. [ 1 ] Use of pre-filled syringes can be the way forward to prevent contamination of drug as well as occupational hazards.…”