Gingival Involvement of Oral Lichen Planus

Camacho-Alonso, Fabio; López‐Jornet, Pía; Bermejo‐Fenoll, Ambrosio

doi:10.1902/jop.2007.060303

Cited by 26 publications

(30 citation statements)

References 16 publications

(18 reference statements)

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“…3,4 Treatment options include potent topical corticosteroids, topical tacrolimus, intralesional corticosteroids, systemic corticosteroids, systemic retinoids, dapsone, mycophenolate mophetil, intravenous immunoglobulins, cyclosporin, and azathioprine. [1][2][3][4] However, these modalities are not always effective or associated with adverse effects when used for sustained periods of time. Our decision to use apremilast for EOLP was based on the mechanism of action of apremilast and the pathogenesis of OLP.…”

Section: Discussionmentioning

confidence: 99%

Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast

AbuHilal

Walsh

Shear

2017

J Dermatol Case Rep

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Background: Erosive oral lichen planus and desquamative gingivitis are uncommon but severe debilitating variants of oral lichen planus. Treatment of these presentations is difficult and challenging. Main observation:A 44-year-old woman was referred to the dermatology clinic with chronic painful lichen planus-related gingivitis and buccal erosions. She has failed multiple treatments including topical clobetasol and tacrolimus, intralesional corticosteroids and several systemic and immunosuppressive agents. Following completion of three months of treatment with oral apremilast at a dose of 30 mg twice daily, significant improvement was noted in her disease activity. Conclusion:Oral apremilast may be a safe and effective treatment for erosive oral lichen planus. (J Dermatol Case Rep. 2016; 10(3): 56-57) Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast

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Section: Discussionmentioning

confidence: 99%

Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast

AbuHilal

Walsh

Shear

2017

J Dermatol Case Rep

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“…A review of previously published studies concluded that the risk of developing squamous cell carcinoma in patients with oral lichen planus was approximately 10 times higher than that in the unaffected general population. The study of the microcirculation in lingual lichen planus (LLP) would be important in the interception of the evolution of LLP (13,14). Capillaroscopy applied to lingual mucosa is a reliable method, useful for study and monitoring of oral lichen planus, if combined with the current conventional methods (15,16).…”

Section: Oral Capillaroscopy and Autoimmune Pathologiesmentioning

confidence: 99%

Oral microcirculation observed in vivo by videocapillaroscopy: a review

2009

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Capillaroscopy is a non-invasive diagnostictechnique that is fundamental in viewing peripheral circulation and in studying microangiopathies. The morphological study of microcirculation is of fundamental importance, mainly because the microvascular bed is directly involved in the etiopathogenesis of autoimmune disorders and acute and chronic inflammatory pathological conditions. The value of capillaroscopic investigation as a diagnostic means in cases of peripheral microcirculation disorders has been confirmed by numerous studies. Other studies used capillaroscopic investigations to evaluate microcirculation damage not as a complication of disease (diabetes), but as its initial stage, and therefore to make a diagnosis. Capillaroscopy is an interesting method of studying microcirculation, because of the possibility of studying small vessels in vivo by means of a microscope. Today, it has become more reliable, thanks to the development of observation tools (photography, videomicroscopy). This review describes in detail various aspects of the microcirculation of the oral mucosa. (J Oral Sci 51, 1-10, 2009)

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“…DG constitutes the gingival manifestation of several mucocutaneous disorders and systemic conditions. It has been reported in association with oral lichen planus (OLP), oral lichenoid lesions, mucous membrane pemphigoid, pemphigus vulgaris, erythema multiforme, graft‐versus‐host disease, lupus erythematosus, paraneoplastic pemphigus, epidermolysis bullosa acquisita, linear IgA disease, chronic ulcerative stomatitis, plasma cell gingivitis, dermatitis herpetiformis, foreign body gingivitis, and psoriasis 2‐15 …”

mentioning

confidence: 99%

Application of a Motivation–Behavioral Skills Protocol in Gingival Lichen Planus: A Short‐Term Study

López‐Jornet¹,

Camacho-Alonso²

2010

Journal of Periodontology

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Gingival Involvement of Oral Lichen Planus

Abstract: Considering the high frequency of gingival involvement in OLP, the diversity of clinical manifestations, and its potential relationship with general and oral health in patients, periodontists should be familiar with the most common clinical aspects of OLP in the gingiva.

Cited by 26 publications

References 16 publications

Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast

Treatment of recalcitrant erosive oral lichen planus and desquamative gingivitis with oral apremilast

Oral microcirculation observed in vivo by videocapillaroscopy: a review

Application of a Motivation–Behavioral Skills Protocol in Gingival Lichen Planus: A Short‐Term Study

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