“…Dental plaque may also exacerbate the condition, and clinical recommendations are consistent in promoting good oral hygiene. Nevertheless, very little evidence exists on the effectiveness of plaque control in OLP management because available data are mainly provided by case reports, case series and cohort studies (Guiglia et al, 2007;Holmstrup, Schiotz, & Westergaard, 1990;Lopez-Jornet & Camacho-Alonso, 2010;Salgado et al, 2013;Scattarella, Petruzzi, Ballini, Grassi, & Nardi, 2011). In 2015, Stone et al published a randomized controlled trial that demonstrated positive effects of plaque reduction in patients with gingival manifestation of OLP, with significant improvement in quality of life and in disease severity score (Stone, Heasman, Staines, & McCracken, 2015).…”