Ginger (Zingiber officinale): An alternative for the prevention of postoperative nausea and vomiting. A meta-analysis

Tóth, Barbara; Lantos, Tamás; Hegyi, Péter; Viola, Réka; Vasas, Andrea; Benkő, Ria; Gyöngyi, Zoltán; Vincze, Áron; Csécsei, Péter; Mikó, Alexandra; Hegyi, Dávid; Szentesi, Andrea; Matuz, Mária; Csupor, Dezső

doi:10.1016/j.phymed.2018.09.007

Cited by 56 publications

(49 citation statements)

References 38 publications

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“…No benefits were observed with aromatherapy blends. Another meta-analysis by Tóth et al 98 investigated the use of ginger for the treatment of PONV, that ginger aromatherapy was associated with slightly reduced nausea severity. Further studies are warranted.…”

Section: Novel Rescue Treatmentmentioning

confidence: 99%

Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies

Jin¹,

Gan²,

Bergese³

2020

TCRM

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Postoperative nausea and vomiting is one of the most frequent adverse events after surgery and anesthesia. It is distressing for the patient and can lead to other postoperative complications. Management of PONV involves a framework of risk assessment, multimodal risk reduction, and prophylactic measures, as well as prompt rescue treatment. There has been a significant paradigm shift in the approach towards PONV prevention. There have also been several emerging therapeutic options for PONV prophylaxis and treatment. In this review, we will discuss the up-to-date PONV management guidelines and highlight novel therapeutic options which have emerged in the last few years.

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Section: Novel Rescue Treatmentmentioning

confidence: 99%

Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies

Jin¹,

Gan²,

Bergese³

2020

TCRM

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“…Ginger is able to reduce nausea and vomiting caused by chemotherapy [108][109][110] through the inhibitory effect of gingerols and shogaols (the main chemical components of ginger) on M3 and 5-HT3 receptors. 111 Peripheral neurotoxicity is one of the main complications associated with the use of chemotherapy agents such as platinum compounds, taxanes, and vinca alkaloids.…”

Section: Phytotherapeutics For Adverse Effectsmentioning

confidence: 99%

Integrative Treatment of Lung Cancer Patients: Observational Study of 57 Cases

Anelli¹,

Nardo²,

Bonucci³

2021

ASJO

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Introduction A retrospective clinical study was performed to identify the characteristics of patients with lung cancer treated with integrative cancer treatment in addition to conventional medicine. Materials and Methods We reviewed medical records for lung cancer patients who visited a single integrative setting in Rome, Italy. A total of 57 patients were included, and the majority had advanced-stage cancer. All of them underwent integrative therapy with nutrition and phytotherapy indications. The diet was designed to reduce most of possible factors promoting cancer proliferation, inflammation, and obesity. Foods with anti-inflammatory, prebiotic, antioxidant, and anticancer properties had been chosen. Herbal supplements with known effects on lung cancer were prescribed. In particular, astragal, apigenine, fucosterol, polydatin, epigallocatechin gallate, cannabis, curcumin, and inositol were used. Furthermore, medical mushrooms and other substances were used to improve the immune system and to reduce chemotherapy side effects. Five key parameters have been evaluated for 2 years starting at the first surgery: nutritional status, immune status, discontinuation of therapy, quality of life, and prognosis of the disease. Results A relevant improvement in parameters relative to nutritional status, immune status, and quality of life has been observed after integrative therapy compared with the same parameters at the first medical visit before starting such approach. Conclusion The results suggest that integrative therapy may have benefits in patients with lung cancer. Even though there are limitations, the study suggests that integrative therapy could improve nutritional status and quality of life, with possible positive effect on overall survival.

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“…Chrubasik et al [2005] reported in a literature review that the efficacy of ginger as an antiemetic is only confirmed in the states of nausea and vomiting during pregnancy [12]. Also, from a meta-analysis which included ten randomized trials published in 2018, the authors concluded that ginger administered per os in different supplements may reduce postoperative nausea and vomiting [43].…”

Section: Gc-ms Analysismentioning

confidence: 99%

Gc-MS Analysis and Bioactive Properties of Zingiberis Rhizoma Essential Oil

Bucur¹

2020

FARMACIA

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Ginger (Zingiber officinalis Roscoe) has been, from the past until now, one of the most worldwide cultivated aromatic plants. The fresh or dried underground ginger rhizome is used in medicinal purposes, which the European Pharmacopoeia presents as Zingiberis rhizoma. The essential oil obtained from ginger, available on the Romanian market, was prepared using the official method with the Neo-Clevenger apparatus. The amount of 1.925% (v/m) ± 0.049 was extracted, which is in accordance with the reference standards of the European Pharmacopoeia. The GC-MS analysis of essential oil composition revealed the presence of camphene (32.79%), eucalyptol (24.32%), α-pinene (18.05 %) and zingiberene (1.25%). Ginger essential oil has antioxidant properties with an IC50 value of 30.72 μL/mL in different acetone dilutions. The antifungal properties highlighted on isolated stems from public spaces (Fonsecaea sp. and Penicillium chrysogenum) may justify the use of ginger essential oil as an agent that prevents the exposure of the population to pathogens. RezumatGhimbirul (Zingiber officinalis Roscoe) a fost şi este una dintre cele mai cultivate plante aromate din lume. În scop medicinal, de la ghimbir se folosește rizomul, proaspăt sau uscat, pe care Farmacopeea Europeană îl prezintă în monografia Zingiberis rhizoma. Uleiul volatil obținut din ghimbirul comercializat pe piața din România, prin metoda oficinală, cu aparatul Neo-Clevenger, este în cantitate de 1,925% (v/m) ± 0,049, ceea ce corespunde prevederilor Farmacopeei Europene, care menționează un conținut de minim 1,5% (v/m). Analiza GC-MS a uleiului volatil a pus în evidență prezența camfenului (32,79%), eucaliptolului (24,32%), α-pinenului (18,05%) și zingiberenului (1,25%). Uleiul volatil de ghimbir prezintă proprietăți antioxidante cu valoarea IC 50 a diluțiilor, în acetonă, de 30,72 µL/mL. Proprietățile antifungice puse în evidență pe tulpini izolate din spațiile publice (Fonsecaea sp. și Penicillium chrysogenum) pot justifica utilizarea uleiului volatil de ghimbir ca agent de prevenire a expunerii populației la agenți patogeni.

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Ginger (Zingiber officinale): An alternative for the prevention of postoperative nausea and vomiting. A meta-analysis

Cited by 56 publications

References 38 publications

Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies

Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies

Integrative Treatment of Lung Cancer Patients: Observational Study of 57 Cases

Gc-MS Analysis and Bioactive Properties of Zingiberis Rhizoma Essential Oil

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