Gigantomastia – a classification and review of the literature

Inferior Pedicle Breast Reduction for the Management of Gestational Gigantomastia: Literature Review and a Case Presentation

“…Till date, there is no approved definition for gigantomastia [2] [3] [4] but most authors have described it as a hypertrophic breast condition in which at least 1.5 kg is resected from each breast during operation [5]. Recently, Dancey et al proposed gigantomastia as excess breast tissue that contributes greater than 3% of patient's total body weight.…”

“…Recently, Dancey et al proposed gigantomastia as excess breast tissue that contributes greater than 3% of patient's total body weight. The disease is termed juvenile gigantomastia in teenagers, idiopathic gigantomastia in adults without any known cause and gestational gigantomastia or pregnancy induced gigantomastia in pregnant women with the disease condition [2].…”

“…Gestational gigantomastia amongst the different types of gigantomastia cases is the least reported (2). Gestational gigantomastia is very rare in women with an incidence rate of 1 in 100,000 pregnancies [6] [2].…”

“…Gestational gigantomastia is very rare in women with an incidence rate of 1 in 100,000 pregnancies [6] [2]. The disease condition has mostly been recorded in Whites, obese and multiparous women [7]; however there have been few cases recorded in Blacks [3] [8]- [17].…”

Mammary-digital-nail (MDN) syndrome: a novel phenotype maps to human chromosome 22q12.3–13.1

“…Over 100 cases of sporadic JHB have been documented. [4][5] Clinical features include bilateral or unilateral rapid breast enlargement, skin hyperemia, and widened subcutaneous veins. 2 The growth of the glands begins between ages 8 and 16, just before or shortly after menarche.…”