Giardia

Smith, H. V.; Paget, Tim

doi:10.1007/978-1-59745-501-5_11

Cited by 6 publications

(1 citation statement)

References 124 publications

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“…Interest in the contamination of drinking water and the pollution of recreational water by protozoan such as Giardia is a major concern to water suppliers and regulatory agencies. − Giardiasis has been implicated in waterborne outbreaks of gastroenteric disease worldwide, ,,, ,, , with Giardia lamblia ( G. lamblia ) responsible for ca. 35% of waterborne parasitic outbreaks that occurred between 2004 and 2010 …”

Section: Introductionmentioning

confidence: 99%

Direct Force Measurement Between Bio-Colloidal Giardia lamblia Cysts and Colloidal Silicate Glass Particles

et al. 2012

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Force-separation measurements between Giardia lamblia cysts and an inorganic oxide (silicate glass) have been obtained by using an atomic force microscope (AFM). The cysts are compressible on the scale of the loads applied during force measurement, with the surface compressibility expressed in terms of an interfacial spring constant (K(int)). The force of interaction prior to this Hookean region, on approach, is long-range and repulsive. The long-range force has been compared to models of the electrical double layer as well as an electrosteric layer. The comparison has led to the conclusion that the cyst surface can be described as a polyelectrolyte brush at intermediate separations (5-115 nm from linear compliance) with an electrical double layer often observed at larger separations. The dependence of the interaction force on surface retraction suggests that tethering between the cyst and siliceous surface can occur. The variation of the interaction with pH and upon variation with ionic strength has also been assessed. The information gained from the measurement of the interaction between G. lamblia and this model sandlike surface informs water treatment processes. Similar studies have been performed by us for the Cryptosporidium parvum (C. parvum) oocyst system to which this work is compared.

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