Giant retroperitoneal liposarcoma measuring 27 × 29 × 36 cm: a case report

Abstract

Retroperitoneal tumors are rare neoplasms that can reach great dimensions due to a slow growth pattern. Although these tumors rarely metastasize, they have a great risk of recurrence, and majority of times these lesions are a challenge for the surgeon. We report the case of a 63-year-old woman who presented with symptoms of large bowel obstruction and was diagnosed with a large heterogenous mass located in the retroperitoneal space. The fine needle biopsy revealed the histology of liposarcoma. The purpose of this article is to report our approach in management of this kind of tumor. Tumor size (27.1 × 29.1 × 36.1 cm) and involvement to the adjacent organs was a challenge for us in order to reach safe oncological margins. In these cases, the risk of recurrence is high; therefore, the patient should be screened at 6, 12 and 24 months post procedure. Chemotherapy or radiotherapy for this tumor is not yet defined, and if operable, surgery is the treatment of choice.

Giant Atypical Spindle Cell Lipomatous Tumor of Retroperitoneal Origin Presenting with Lung Metastasis and Extension to the Thigh: A Case Report with Literature Review

“…RPS have an overall expected yearly incidence of 0.5 to 1 per 100,000 individuals. 8 LS is the most frequent type of STS, and includes four major histological types, including atypical lipomatous tumor/well-differentiated LS, myxoid/round cell LS, dedifferentiated LS, and pleomorphic LS. 11 Additionally, the well-differentiated LS has five variants, including sclerosing, lipoma-like, inflammatory, liposarcoma with meningothelial whorls, and spindle cell.…”

“…3,[5][6][7] Patients with sarcoma are generally asymptomatic, and have a painless mass (15-18 cm) at presentation. 8 Rarely, the patient presents with distant metastasis, particularly in the lungs. 5 Computed tomography (CT) of the abdomen and pelvis as well as thorax is sufficient to reach the diagnosis, and assess the distant metastasis, respectively.…”

Lipossarcoma retroperitoneal: a importância do diagnóstico precoce e fatores prognósticos

“…Brazilian Journal of Health Review, Curitiba, v. 6, n. 3, p. 12704-12713, may./jun., 2023 Os casos mais frequentes de urgência oncológica por lipossarcoma retroperitoneal descritos na literatura envolvem a compressão realizada pelo tumor, devido a suas grandes dimensões. Entre as complicações descritas estão os casos de obstrução intestinal 1,8 , insuficiência renal 24 e pancreatite aguda pela compressão de porção do duodeno e ampola de Vater 15 . Em uma análise retrospectiva com 20 casos de lipossarcoma retroperitoneal, 15 pacientes apresentaram urgência oncológica, sendo 13 casos por obstrução intestinal 14 .…”