Giant pseudopolyps in granulomatous colitis

Abstract

A case of giant localized pseudopolyp causing partial large-bowel obstruction and occurring in granulomatous colitis is reported. This represented the first manifestation of the patient's disease. The role of surgery in certain patients is discussed.

Giant Pseudopolyposis in Inflammatory Bowel Disease

“… 10 More than 70 cases of giant pseudopolyposis associated with inflammatory bowel disease have been reported. 2,4–7,10–42 The presence of pseudopolyps per se does not reflect the severity of the underlying inflammatory bowel disease and may be found in both active and quiescent phases of ulcerative colitis. 2 The reported duration of ulcerative colitis and Crohn’s colitis, in whom pseudopolyposis is found, ranges, respectively, from 1 month to 20 years (median, 5 years) 2,4,10–34 and 3 months to 37 years (median, 6 years).…”

Colocolonic Intussusception of a Giant Pseudopolyp in a Patient With Ulcerative Colitis

“…9,10 This is especially relevant when treating patients with IBD who are at increased risk of developing a malignancy. 11 While giant pseudopolyps generally do not appear to have malignant potential, 8,12,13 occult malignancy within a giant pseudopolyp has been reported. 14 Extreme vigilance, including colonoscopy with biopsy and careful radiographic follow‐up, to exclude malignancy is mandatory in this patient population.…”

Sonographic appearances of conglomerated polyps (giant polyposis) in patients with Crohn's disease

“…Giant polyposis is usually misdiagnosed as colon cancer [3][4][5][6]8,[15][16][17] or villous adenoma 5,6,13,16 on radiologic examination. This is so whether the giant polyposis is associated with symptoms of acute obstruction 4 or represents the only manifestation of CD; it is especially so when the giant polyposis causes stenosis that impairs radiologic evaluation, endoscopy, and biopsy.…”

“…This is so whether the giant polyposis is associated with symptoms of acute obstruction 4 or represents the only manifestation of CD; it is especially so when the giant polyposis causes stenosis that impairs radiologic evaluation, endoscopy, and biopsy. 2,13,15 Most patients with giant polyposis undergo surgery based on the presumed diagnosis of colon cancer, on the presence of obstructive symptoms, or both. 2,4,9,13 The sonographic findings in patients with giant polyposis correlate well with the histologic characteristics and clinical course of this form of CD.…”

“…2,13,15 Most patients with giant polyposis undergo surgery based on the presumed diagnosis of colon cancer, on the presence of obstructive symptoms, or both. 2,4,9,13 The sonographic findings in patients with giant polyposis correlate well with the histologic characteristics and clinical course of this form of CD. High-frequency and even good low-frequency scanners allow identification of 5 layers in the loops of almost all of the hollow viscera.…”