Giant Pseudopolyposis in Inflammatory Bowel Disease

Ooi, B. S.; Tjandra, Joe J.; Pedersen, John; Bhathal, Prithi S.

doi:10.1046/j.1440-1622.2000.01826.x

Cited by 29 publications

(39 citation statements)

References 34 publications

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“…Localized giant pseudopolyposis is a well-documented although uncommon occurrence in IBD (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). It has been described in both active and quiescent phases of disease, in all colonic segments and tends to occur early in the course of IBD (3,(10)(11)(12).…”

Section: Discussionmentioning

confidence: 99%

“…It has been described in both active and quiescent phases of disease, in all colonic segments and tends to occur early in the course of IBD (3,(10)(11)(12). Clinical symptoms are not usually related to the lesion but rather to disease activity itself, although colonic obstruction and intussusception have been reported (16,19).…”

Section: Discussionmentioning

confidence: 99%

“…Clinically, endoscopically and radiologically, these masses have commonly been mistaken for neoplastic lesions (3,11,12,15,17,21). The dilemma revolves around confidently differentiating a giant pseudopolyp from a villous adenoma, dysplasiaassociated lesion or mass, or polypoid carcinoma.…”

Section: Discussionmentioning

confidence: 99%

“…Localized giant pseudopolyposis of the colon is a rare complication of inflammatory bowel disease (IBD), defined as a pseudopolyp (isolated or clustered) larger than 1.5 cm (3,4). There are more than 75 reported cases in the literature (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20), but only one report of an occult carcinoma associated with such a lesion (20) and no reports of associated dysplasia. A case of a giant pseudopolyp containing occult dysplasia in the absence of adenomatous tissue in a patient with Crohn's colitis is presented.…”

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confidence: 99%

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Occult Dysplasia in a Localized Giant Pseudopolyp in Crohn’s Colitis: A Case Report

Wyse

Lamoureux

Gordon

et al. 2009

Canadian Journal of Gastroenterology

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Localized giant pseudopolyposis of the colon (pseudopolyp larger than 1.5 cm in size) is a rare complication of inflammatory bowel disease. There is one report of an occult carcinoma within such a lesion, and no reports of sole dysplasia. A case of a 42-year-old man with longstanding Crohn’s colitis who underwent a colonoscopy revealing a large, multilobulated mass at the splenic flexure that was not amenable to endoscopic removal, is described. Multiple biopsies showed no dysplasia and histology was consistent with an inflammatory pseudopolyp. Computed tomographic colonography demonstrated a mass resembling a large villous tumour. A decision for surgery was made. The surgical specimen was a complex anastomosing inflammatory pseudopolyp 5 cm × 4 cm × 3 cm in size, with a focus of low-grade dysplasia in an area free of inflammation.The present case is the first reported occult dysplasia in a giant pseudopolyp. Occult dysplasia without superficial dysplasia may exist in these lesions and further studies are needed to examine risk factors that make a giant pseudopolyp more likely to harbour dysplasia and/or carcinoma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Occult Dysplasia in a Localized Giant Pseudopolyp in Crohn’s Colitis: A Case Report

Wyse

Lamoureux

Gordon

et al. 2009

Canadian Journal of Gastroenterology

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“…What is of importance is that in patients with a long history of UC, the existence of a dysplasia associated lesion or mass (DALM) is very probable, and only precise, multiple biopsies can distinguish between DALM's and 'normal' pseudopolyps. However, based on over 70 reported cases in the literature where no dysplastic changes and only one adenocarcinoma associaded with pseudopolyps was found, the possibility of DALM or/and malignancy is relatively low [1,4,[8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. Although pseudopolyps themselves are benign, the existence of pseudopolyps is known to be an independent marker of increased risk of colorectal carcinoma in UC.…”

Section: Discussionmentioning

confidence: 99%

Giant Localized Pseudopolyp of the Colon as the First Manifestation of Inflamatory Bowel Disease: A Case Report and Literature Review

Filip¹,

Radzki²,

BieÅko³

et al. 2014

J Gastroint Dig Syst

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Pseudo polyps are very common in the course of ulcerative colitis and Crohn's disease. Patients with long history of inflammatory bowel disease are known to be at higher risk of malignancy. Giant colonic psedopolyps are sometimes mistaken for carcinoma which may potentially lead to unnecessary surgery. We describe a case of a 62-year-old man with a large localized inflammatory lesion of the sigmoid colon. The clinical presentation of this rare tumor-like lesion, which can be considered as a localized giant pseudo polyp of the colon, mimicked malignancy or polypoid cavernous hemangioma. What is also unique in this case, is that no definite past history of inflammatory bowel disease could be demonstrated.

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Endoscopic view of rectal amebiasis mimicking a carcinoma

Ooi

Seow‐Choen

2003

Techniques in Coloproctology

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We report the case of a 45-year-old man with rectal amebiasis, presenting with rectal bleeding and chronic diarrhea, confirmed on rectal biopsy. The endoscopic view was highly suggestive of a carcinoma and caused confusion about its etiology. The striking difference in the endoscopic view before and after medical therapy of the tumor-like lesion was remarkable. This case illustrates the importance of an accurate histologic diagnosis before definitive treatment and highlights the mimicry of rectal carcinoma by rectal amebiasis on endoscopy.

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Giant Pseudopolyposis in Inflammatory Bowel Disease

Cited by 29 publications

References 34 publications

Occult Dysplasia in a Localized Giant Pseudopolyp in Crohn’s Colitis: A Case Report

Occult Dysplasia in a Localized Giant Pseudopolyp in Crohn’s Colitis: A Case Report

Giant Localized Pseudopolyp of the Colon as the First Manifestation of Inflamatory Bowel Disease: A Case Report and Literature Review

Endoscopic view of rectal amebiasis mimicking a carcinoma

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