Giant onychomatricoma: report of two cases with rare clinical presentation

Estrada-Chávez, Guadalupe; Vega‐Memije, María Elisa; Toussaint–Caire, Sonia; Rangel, Lauren K.; Domínguez‐Cherit, Judith

doi:10.1111/j.1365-4632.2007.03300.x

Cited by 30 publications

(25 citation statements)

References 8 publications

(13 reference statements)

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“…Giant OM similar to our case has been sparsely reported in the literature [29,30,31]. Delay of diagnosis and associated recurrent trauma have been hypothesized to promote tumor growth, rendering the differential diagnosis more difficult.…”

Section: Discussionsupporting

confidence: 55%

Giant Onychomatricoma of the Great Toenail: Case Report and Review Focusing on Less Common Variants

Prevezas

Triantafyllopoulou

Belyayeva

et al. 2015

Skin Appendage Disord

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Onychomatricoma is a rare benign fibroepithelial filamentous tumor originating from the nail matrix. It typically presents with the clinical tetrad of xanthonychia, pachyonychia, proximal splinter hemorrhages and increased transverse overcurvature of the nail plate. The giant variant can easily confuse the clinician due to its extensive nail dystrophy that can mask the characteristic features of this tumor. Benign (fibrokeratoma, ungual fibroma, onycholytic matricoma) and malignant entities (Bowen's disease, squamous cell carcinoma, onycholytic carcinoma) are mimics of the disease. Nail surgery can facilitate the diagnosis, which should always be confirmed by histology, as rare variants do exist.

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Section: Discussionsupporting

confidence: 55%

Giant Onychomatricoma of the Great Toenail: Case Report and Review Focusing on Less Common Variants

Prevezas

Triantafyllopoulou

Belyayeva

et al. 2015

Skin Appendage Disord

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“…Most of the reports on onychomatricoma present tumors found only in a portion of the nail plate, demonstrated by a superficial band-like pattern of yellowish discoloration with increased transverse curvature of the nail. To date there have been 5 reported cases of giant onychomatricoma (Table 1), all of them with a history of prior trauma [10,11,12,13]. Interestingly, all tumors were found to be located on the great toenail or thumbnail, which are areas that are potentially more susceptible to trauma.…”

Section: Discussionmentioning

confidence: 99%

Onychomatricoma: A Rare Nail Tumor with an Unusual Clinical Presentation

Kamath

Villada

et al. 2017

Skin Appendage Disord

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First described in 1992, onychomatricoma is a rare, benign, fibroepithelial tumor of the nail matrix with few reported cases in the literature. The tumor predominately affects the fingers of Caucasian women during the 5th decade of life and is typically slow growing and painless. The authors present a unique clinical presentation of a giant onychomatricoma in a darker-skinned 60-year-old South Asian individual who presented with a large dome-shaped nail that was smooth, shiny, and green.

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“…A frontal view of the nail typically reveals multiple holes in the thickened free margin. Tumors may affect the entire nail matrix and nail plate, with the authors of one article suggesting the name "giant onychomatricomas" for this variant [4]. Potentially misleading clinical Clinical Image findings, such as verrucous surface, total dystrophy of the nail unit, and a pseudofibrokeratoma appearance, have been reported as well.…”

mentioning

confidence: 99%

“…The rarity of this entity and possible confusion due to less than classic clinical presentation may require further workup. Diagnosis may not be obvious until surgery is performed, at which point the typical filiform projections are more visible [4]. Pathologists may be faced with making the diagnosis without the nail plate, as it is often not submitted.…”

mentioning

confidence: 99%