Giant hepatic angiomyolipoma

Ohmori, Takaaki; Arita, Norimasa; Uraga, Naomi; Tabei, Ryo; Yamamoto, M.; Kataoka, Makoto; Hamamoto, Ken

doi:10.1111/j.1365-2559.1989.tb01615.x

Cited by 31 publications

(25 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A summary of these cases is shown in Table 1. Although, as Nonomura et al [7] reported, 24 of 39 (62%) hepatic AMLs with an invasive growth pattern into the surrounding parenchyma and along the portal and hepatic veins showed no malignant behavior, there were more than 9 cases of AML which may have had malignant potential [3,[8][9][10][11][12][13][14][15]. Our further review of these nine cases revealed that although an invasive pattern was found in almost all cases, 3 of 4 cases (Cases 2, 6-8) [9,[13][14][15] which showed portal vein thrombosis had a significantly severe prognosis, with 75% mortality, caused by multiple recurrences and metastases in the liver (Cases 2, 7, 8), peritoneum (Cases 2, 7), retroperitoneal region (Case 7), gastrohepatic omentum (Case 7), pancreas (Case 8), and lung (Case 8) [9,14,15].…”

Section: Discussionmentioning

confidence: 97%

“…Misdiagnosis of this tumor has been focused on in various articles; however, since 2000, several reports have revealed that hepatic AMLs can become malignant, metastasize, enlarge, and recur [3,5,[8][9][10][11][12][13][14][15]. In 1989, Ohmori et al [8] reported the first possibly malignant case, which increased in size to 18 cm and caused liver dysfunction and bronchopneumonia with exacerbating hepatomegaly, resulting in the patient's death. Dalle et al [9] reported a case in a 70-yearold woman, in whom the tumor showed a size increase from 15 to 26 cm in 5 years and metastasis in the lower abdomen.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Malignant potential of hepatic angiomyolipoma: case report and literature review

Kamimura

Oosaki

Sugahara

et al. 2010

Clin J Gastroenterol

View full text Add to dashboard Cite

Hepatic angiomyolipoma (AML) is known as a rare benign tumor with invasive growth. In the past, some of these tumors were misdiagnosed as hepatocellular carcinomas, because of the similar pattern on imaging studies. Recently, correct diagnoses have been increasing, with the development of HMB-45 immunohistochemical staining, and it appears that the majority of these tumors behave as benign tumors. However, there are not a few cases which have resulted in fatal courses because of recurrence and metastasis of the tumor. The clinical features and signs of the malignant potential of this tumor are unknown; thus, the management and treatment of the tumor are still controversial. Here in this article, we report a case of hepatic AML which showed a size increase of 175% in 1 year, and portal vein thrombosis detected by angiography. During a follow up of 3 years after a curative hepatic lobectomy, no metastasis or recurrence was seen. Review of the literature suggests that portal vein thrombosis could be one of the markers of the malignant potential and transformation of this tumor. Therefore, in this paper, we recommend surgical treatment of hepatic AML in which there is a strong suspicion of portal vein thrombosis.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Malignant potential of hepatic angiomyolipoma: case report and literature review

Kamimura

Oosaki

Sugahara

et al. 2010

Clin J Gastroenterol

View full text Add to dashboard Cite

show abstract

“…In 20 of these the cross-sectional imaging findings were reported [2, 4-8, 11, 13, 16-18, 25-28], whereas the other 29 were published in surgical or pathologic papers [9,10,12,14,15,[19][20][21][22][23][24][29][30][31].…”

Section: Introductionmentioning

confidence: 99%

Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review

1997

View full text Add to dashboard Cite

Angiomyolipoma is an uncommon lipomatous neoplasm of the liver, usually asymptomatic and identified incidentally. We describe the CT findings of a surgically confirmed case of spontaneously ruptured angiomyolipoma with evidence of internal hemorrhage and hemoperitoneum. The CT features were that of an exophitic, oval, well-defined mass with inhomogeneous attenuation values due to the presence of fat- and soft-tissue densities. A review of the literature identified 49 cases of hepatic angiomyolipoma. Few of these occurred in symptomatic patients and showed intratumoral hemorrhagic foci, but none had a clear rupture with external bleeding. To our knowledge, this is the first reported case with this complication.

show abstract

“…Since this benign tumor was first described by Ishak in 1976 (1), only 52 cases have been reported (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Patients with these tumors did not usually manifest clinical symptoms.…”

Section: Introductionmentioning

confidence: 99%

Giant Hepatic Angiomyolipoma Associated with Disseminated Intravascular Coagulation.

et al. 1997

View full text Add to dashboard Cite

Wereport a case of giant hepatic angiomyolipomain a 68-year-old womanwhohad an increase in the fibrinolytic activity concomitant with disseminated intravascular coagulation (DIC). The presence of the tumor was confirmed by ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomenand the selective arteriography of the liver via the superior mesenteric artery. Following treatment with heparin and gabexate mesilate, abnormal hemostatic values were corrected. Furthermore, the surgical removal of the huge hepatic angiomyolipomacompletely normalized the alternations of the clotting system. These findings suggest that giant hepatic angiomyolipoma was profoundly associated with DIC.

show abstract

Giant hepatic angiomyolipoma

Cited by 31 publications

References 2 publications

Malignant potential of hepatic angiomyolipoma: case report and literature review

Malignant potential of hepatic angiomyolipoma: case report and literature review

Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review

Giant Hepatic Angiomyolipoma Associated with Disseminated Intravascular Coagulation.

Contact Info

Product

Resources

About