Giant cell tumour of the femoral neck: Failure of curettage–cavity filling cementation with screw fixation, a case report

Abdulrazak, S.; Marzouki, A.; Bah, Souleymane Thierno; Lahrach, K.; Boutayeb, F.

doi:10.1016/j.tcr.2019.100216

Cited by 3 publications

(4 citation statements)

References 24 publications

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“…Surgery is the mainstay of treatment for resectable GCT, aiming to achieve local tumor control and preserve joint function. In patients with recurrent cases, it is important to consider limb salvage [ 8 ]. In our study, we witnessed a case of recurrent GCT in the right proximal femur, which was treated with limb salvage using an endoprosthesis.…”

Section: Discussionmentioning

confidence: 99%

The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

Kumar,

Mittemari,

Nimmagadda

et al. 2023

Cureus

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Introduction The proximal femur is a common site for primary bone sarcomas, including Ewing's sarcoma, chondrosarcoma, osteosarcoma, and giant cell tumors (GCT). Extensive resections are challenging to reconstruct because the size of the tumor may necessitate an extensive resection of the femur to achieve adequate oncologic clearance. The resection of the proximal femur can result in hip joint instability due to the loss of the strong native hip capsule or hip abductor strength. With a wide range of reconstruction options, such as resection arthrodesis, allograft-prosthetic composite (APC), and endoprosthesis, we can achieve limb salvage with good functional outcomes. Objective The objective of this case series is to evaluate the clinical outcomes and complications associated with endoprosthesis replacement in patients with proximal femur tumors. Methods A prospective analysis was conducted with 32 patients who underwent modular endoprosthesis replacement for proximal femoral tumors at our institution. Patient data, tumor characteristics, surgical details, and postoperative outcomes were collected and analyzed. Results The study involved 32 patients who met the inclusion criteria. They were assessed using the Musculoskeletal Tumor Society Score (MSTS), which showed good functional outcomes in 72.84% of the patients. The study highlights the functional outcomes and potential complications associated with the use of modular prostheses. Conclusion Endoprosthesis replacement in proximal femur tumors is a viable treatment option, providing good functional outcomes and an acceptable method for limb salvage, which enhances the quality of life.

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Section: Discussionmentioning

confidence: 99%

The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

Kumar,

Mittemari,

Nimmagadda

et al. 2023

Cureus

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“…We identified 10 articles ( Table 1 ), four of which were case studies [ 4 , 5 , 7 , 8 ]. The other six were case series.…”

Section: Discussionmentioning

confidence: 99%

“…Proximal femoral tumors have been infrequently reported in the literature [ 3 ]. GCT is a benign tumor that may become locally invasive leading to extensive bony destruction [ 4 , 5 ]. Surgical management is the first line of treatment for relieving symptoms, preventing local recurrence, and improving overall patient survivorship [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Giant Cell Tumor of the Femoral Head: A Case Report and Review of the Literature

Elbardesy¹,

Sheridan²,

Guerin³

2021

JOCR

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Introduction: Giant cell tumors (GCTs) of the bone are uncommon primary bone neoplasms that occur mainly in the epiphysis of long bones. GCT of the femoral head is rarely encountered. Case Report: We report a rare case of GCT of the femoral head in a 20-year-old female. The patient presented with pathological fracture. The patient underwent total hip arthroplasty (THA). The aim of this paper is to present a case study with pathological fracture of the femoral head and to report the results of a literature review. Conclusion: The treatment of choice for GCT of the proximal femur is a hip arthroplasty with either a standard THA for small confined tumors or endoprosthesis insertion for more extensive tumors. Joint preserving procedures have a high revision rate (47.06%). Denosumab has been tried as a neoadjuvant treatment with some success in certain cases. Keywords: Giant cell tumor, pathological fracture, arthroplasty.

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“…1,2 Proximal femoral giant cell tumors are rather rare and being locally aggressive are at a high risk of pathological fractures. 3 Histology of these tumors comprises majority stromal cells with giant cells having osteoclastic activity. Certain cases may present with distal metastasis and significant incidence of local recurrence.…”

Section: Introductionmentioning

confidence: 99%

A case of proximal femoral giant cell tumor treated with total hip arthroplasty following a pathological fracture

Paigude,

Bartakke,

Lakde

et al. 2023

IJOS

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Giant cell tumors occurring in the proximal femoral region are rather rare and present as challenges to physicians due to their aggressive nature leading to pathological fractures. Preservation of the hip joint is rather difficult due to their affinity to the periarticular area. As per vast literature search, reconstruction of the proximal femoral region using total hip arthroplasty provide favorable results compared to hip preservation in terms of functional outcomes and reduced recurrence rates. Hereby, we present our experience in a case of proximal femoral giant cell tumor managed with total hip arthroplasty following pathological fracture.

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Giant cell tumour of the femoral neck: Failure of curettage–cavity filling cementation with screw fixation, a case report

Cited by 3 publications

References 24 publications

The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

Giant Cell Tumor of the Femoral Head: A Case Report and Review of the Literature

A case of proximal femoral giant cell tumor treated with total hip arthroplasty following a pathological fracture

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