Giant Cell Arteritis

Pineles, Stacy L.; Arnold, Anthony C.

doi:10.1097/iio.0b013e318157fb08

Cited by 14 publications

(23 citation statements)

References 81 publications

(106 reference statements)

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“…The diagnosis of GCA was made on clinical grounds [5]. Although, TAB is the gold standard diagnostic tool for GCA [13], due to segmental disease [2,16] and to the high risk of immediate visual loss, systemic high dose steroid therapy was initiated urgently, before the histopathology result was available. TAB is most beneficial when there is a degree of diagnostic uncertainty, an atypical presentation or when highdose systemic steroids may be contraindicated, such as osteoporosis or diabetes [11].…”

Section: Discussionmentioning

confidence: 99%

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Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

Damian¹

2022

Case Rep Int

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Introduction:Anterior optic ischemic neuropathy (AOIN) is the most frequent cause of visual loss in giant cell arteritis (GCA). As blindness is rarely reversible, the main therapeutic goal is to prevent bilateral disease by immediate initiation of high-dose intravenous steroids. Approximately, one third of patients present with bilateral visual impairment. Case Report: A 77-year-old patient, came to the Ophthalmology Emergency Room for sudden loss of vision in the left eye (OS) to no light perception (NLP) with two days duration and significant narrowing of the visual field in the right eye (OD) with 10 hours duration. Fundus examination revealed swelling and pallor of the optic disc in both eyes (OU). Laboratory examination showed elevated ESR (56 mm/h) and CRP (5.24 mg/dl). Temporal artery biopsy (TAB) proved granulomas and fibrosis within the vessel wall. Immediate Methylprednisolon 1 gm was administered intravenously for five days, followed by oral Prednisone 1mg/kg for four weeks with tapering of 10 mg per month. The patient was put on diabetic and low sodium regimen. During the 3rd day of treatment, vision OD dropped to NLP. Despite continuing systemic steroid therapy, vision remained

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Section: Discussionmentioning

confidence: 99%

“…Giant cell arteritis (GCA) was first described by Hutchinson in 1890 [1,2], but the first histological evidence was presented by Horton in 1932 [2][3][4]. GCA touches typically the branches of the extracranial carotid artery: ophthalmic, posterior ciliary and superficial temporal [5,6].…”

Section: Introductionmentioning

confidence: 99%

Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

Damian¹

2022

Case Rep Int

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“…25,51,63 Pallor of the optic disc is seen in all patients. extensive loss of the neuroretinal rim occurs, and the remaining rim appears pale.…”

Section: ▶ Reviewsmentioning

confidence: 95%

The optic nerve head in acquired optic neuropathies

et al. 2010

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Acquired optic neuropathies are a common cause of blindness in adults, and are associated with characteristic morphological changes at the optic nerve head. Accurate and prompt clinical diagnosis, supplemented with imaging where appropriate, is essential to optimize management of the optic neuropathy and to counsel the patient appropriately on its natural history. History taking, optic disc findings, visual field assessment and imaging of the nerve head and surrounding retinal nerve fiber layer are all paramount to achieving the correct diagnosis. This Review highlights the optic nerve head features that are common to the acquired optic neuropathies, and describes the features that can be used to differentiate these various conditions.

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“…Eine Diplopie wurde nach Literaturangaben von 6-12% der RZA-Patienten angegeben [17]. Das gemeinsame Auftreten von Diplopie und Hepatitis als initiale Befunde einer RZA ist ungewöhnlich [12].…”

Section: Diplopieunclassified

Augenbefunde und Differenzialdiagnosen bei Riesenzellarteriitis (Arteriitis cranialis)

Schmidt¹,

Neß²

2009

Z. Rheumatol.

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Giant Cell Arteritis

Cited by 14 publications

References 81 publications

Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

The optic nerve head in acquired optic neuropathies

Augenbefunde und Differenzialdiagnosen bei Riesenzellarteriitis (Arteriitis cranialis)

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