Giant cell angiofibroma of the mediastinum

Fukunaga,; Ushigome,

doi:10.1046/j.1365-2559.1998.0285g.x

Cited by 23 publications

(10 citation statements)

References 6 publications

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“…described seven cases of a distinctive orbital tumour occurring in middle‐aged adults and introduced the term ‘giant cell angiofibroma’ (GCA) of the orbit. Following its initial description, similar lesions have been described in extra‐orbital locations including the posterior mediastinum, 35 the submandibular and parascapular regions, 34,36 the parotid gland, 37 the retroperitoneum, the scalp and the vulva 36 . Subsequently, with experience, many similarities were noted between GCA and SFT.…”

Section: Extrapleural Solitary Fibrous Tumour and Related Lesionsmentioning

confidence: 85%

“…Some reported cases of giant cell‐rich SFT show stromal myxoid changes or keloidal collagen deposition reminiscent of amianthoid fibres described in more conventional SFT. Immunohistochemically, tumour cells, including the multinucleated giant cells, are generally strongly and diffusely positive for CD34 35–37 . Most lesions also show immunoreactivity for CD99 and bcl‐2 (80%), 36,37 paralleling the immunoprofile of conventional SFT.…”

Section: Extrapleural Solitary Fibrous Tumour and Related Lesionsmentioning

confidence: 97%

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Solitary fibrous tumour and haemangiopericytoma: evolution of a concept

2005

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Haemangiopericytoma (HPC) was described in 1942 by Stout and Murray as a distinctive soft tissue neoplasm, presumably of pericytic origin, exhibiting a characteristic well-developed "staghorn" branching vascular pattern. Over the years, it appeared that this growth pattern was a non-specific one, shared by numerous, unrelated benign and malignant lesions, and that HPC was better considered as a diagnosis of exclusion. Three categories of lesion may now be individualized within the heterogeneous group of HPC-like neoplasms. The first category corresponds to those non-HPC neoplasms that occasionally display HPC-like features (e.g. synovial sarcoma). Lesions belonging to the second category show clear evidence of myoid/pericytic differentiation and correspond to true HPCs. They generally show a benign clinical course, and include glomangiopericytoma/myopericytoma, infantile myofibromatosis (previously called infantile HPC), and a subset of sinonasal HPCs. The third category is the solitary fibrous tumour (SFT) lesional group, which includes fibrous-to-cellular SFTs, and related lesions such as giant cell angiofibromas and lipomatous HPCs. In practice, any HPC-like lesion can be allocated to one of these categories, leaving the ill-defined "haemangiopericytoma" category empty.

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Section: Extrapleural Solitary Fibrous Tumour and Related Lesionsmentioning

confidence: 85%

Section: Extrapleural Solitary Fibrous Tumour and Related Lesionsmentioning

confidence: 97%

Solitary fibrous tumour and haemangiopericytoma: evolution of a concept

2005

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“…, 1 the lesion was described as a unique orbital tumour but, in an addendum, the authors also recorded a non‐orbital tumour in the buccinator fascia of the cheek in a 40‐year‐old man. More recently, there have been reports of 16 other extraorbital giant cell angiofibromas, 2–8 the main features of which are tabulated in Table 3. Most of these tumours had a rather long clinical history and occurred in adults.…”

Section: Discussionmentioning

confidence: 99%

“…in 1995 as a rare, potentially recurring orbital tumour occurring exclusively in adults. Subsequently, 16 cases have been observed in extra‐orbital sites 2–8 …”

Section: Introductionmentioning

confidence: 99%

A study of four cases of extra‐orbital giant cell angiofibroma with documentation of some unusual features

et al. 2001

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“…A dacryocystectomy and medial maxillectomy were performed. Giant cell angiofibroma has also been described in the retroauricular region, submandibular region, 7 scapular region, 7 back, 8 axillary and groin regions, 9 parotid gland, 9 scalp, neck, mediastinum, 10 retroperitoneum, and vulva. 6 Two cases of GCA in the buccal mucosa have been described as well.…”

Section: Report Of a Casementioning

confidence: 99%