Getting the Most from the Host: How Pathogens Force Plants to Cooperate in Disease

Hok, Sophie; Attard, Agnès; Keller, Harald

doi:10.1094/mpmi-04-10-0103

Cited by 50 publications

(36 citation statements)

References 86 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The principal assumption is that a susceptible host will support microbial growth inside host tissues, leading eventually to the development of symptoms and disease. Inversely, non-susceptible (resistant) hosts will block pathogen infection and the expression of disease (Casadevall and Pirofski, 2001; Hok et al, 2010). Compatible host-microbe interactions, however, do not always result in overt negative effects, and asymptomatic or cryptic fungal infections are increasingly recognized as a common feature of many symbiotic associations between fungi and their hosts (Rodriguez et al, 2009; Porras-Alfaro and Bayman, 2011; Malcolm et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Cryptic fungal infections: the hidden agenda of plant pathogens

Stergiopoulos

Gordon

2014

Front. Plant Sci.

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Cryptic fungal infections: the hidden agenda of plant pathogens

Stergiopoulos

Gordon

2014

Front. Plant Sci.

View full text Add to dashboard Cite

“…Pathogens also reprogram host physiological functions to enhance susceptibility. For example, bacterial and fungal pathogens that enter leaves via stomatal apertures secrete molecules that block stomatal closure (Hok et al, 2010). A further extension of host reprogramming by pathogens is where host processes regulated by growth hormones such as auxins, gibberellins, and cytokinins, are modified by pathogens either by the production of functional hormone analogs by the pathogen itself or via modification of endogenous hormone levels (Robert-Seilaniantz et al, 2007;Grant and Jones, 2009).…”

mentioning

confidence: 99%

The Lateral Organ Boundaries Domain Transcription Factor LBD20 Functions in Fusarium Wilt Susceptibility and Jasmonate Signaling in Arabidopsis

et al. 2012

View full text Add to dashboard Cite

The LATERAL ORGAN BOUNDARIES (LOB) DOMAIN (LBD) gene family encodes plant-specific transcriptional regulators functioning in organ development. In a screen of Arabidopsis (Arabidopsis thaliana) sequence-indexed transferred DNA insertion mutants, we found disruption of the LOB DOMAIN-CONTAINING PROTEIN20 (LBD20) gene led to increased resistance to the root-infecting vascular wilt pathogen Fusarium oxysporum. In wild-type plants, LBD20 transcripts were barely detectable in leaves but abundant in roots, where they were further induced after F. oxysporum inoculation or methyl jasmonate treatment. Induction of LBD20 expression in roots was abolished in coronatine insensitive1 (coi1) and myc2 (allelic to jasmonate insensitive1) mutants, suggesting LBD20 may function in jasmonate (JA) signaling. Consistent with this, expression of the JA-regulated THIONIN2.1 (Thi2.1) and VEGETATIVE STORAGE PROTEIN2 (VSP2) genes were up-regulated in shoots of lbd20 following treatment of roots with F. oxysporum or methyl jasmonate. However, PLANT DEFENSIN1.2 expression was unaltered, indicating a repressor role for LBD20 in a branch of the JA-signaling pathway. Plants overexpressing LBD20 (LBD20-OX) had reduced Thi2.1 and VSP2 expression. There was a significant correlation between increased LBD20 expression in the LBD20-OX lines with both Thi2.1 and VSP2 repression, and reduced survival following F. oxysporum infection. Chlorosis resulting from application of F. oxysporum culture filtrate was also reduced in lbd20 leaves relative to the wild type. Taken together, LBD20 is a F. oxysporum susceptibility gene that appears to regulate components of JA signaling downstream of COI1 and MYC2 that are required for full elicitation of F. oxysporum-and JA-dependent responses. To our knowledge, this is the first demonstration of a role for a LBD gene family member in either biotic stress or JA signaling.

show abstract

“…This tug-of-war between plants and pathogens is represented as a zig-zag-zig model. [5][6][7] Both PTI and ETI cause stomatal closure and hypersensitive response (HR), a programmed host cell death (PCD) to limit pathogen development. 5,8 Proteases play important roles in plant innate immunity.…”

mentioning

confidence: 99%

The role of vacuolar processing enzymes in plant immunity

Zhang

Zheng

2010

Plant Signaling & Behavior

View full text Add to dashboard Cite

In the course of their development, plants have had to face a wide range of potential pathogens, including viral, bacterial, fungal and oomycete pathogens. Plants, unlike animals, which have specialized defender cells and an adaptive immune system, have an innate immunity of each cell and produce systemic signals emanating from the infection site. The plant innate immunity (PTI) is induced by pathogen-associated molecular patterns (PAMPs) 1 and elicitors. 2,3 However, some pathogens deliver virulence proteins that target host protein to overcome the plant immunity response. Most plants have evolved the corresponding resistance (R) protein to recognize effector activity, which will trigger plant resistance through effector-triggered immunity (ETI). 4 Natural selection drives evolution of new pathogen effector proteins and plant R proteins. This tug-of-war between plants and pathogens is represented as a zig-zag-zig model. [5][6][7] Both PTI and ETI cause stomatal closure and hypersensitive response (HR), a programmed host cell death (PCD) to limit pathogen development. 5,8 Proteases play important roles in plant innate immunity. in this mini-review, we describe the current view on the role of a plant protease, vacuolar processing enzyme (vPe), and the first identified plant caspase-1-like protein, in plant immunity. in the past several years, vPes were determined to play important roles in various types of cell death in plants. early studies demonstrated the identification of vPe as a vacuolar hydrolytic protein responsible for maturation of vacuolar proteins. Later, Nicotiana benthamiana vPe was reported to mediate virusinduced hypersensitive response by regulating membrane collapse. The ortholog of vPe in Arabidopsis is also suggested to be involved in both mycotoxin-induced cell death and developmental cell death. However, the role of vPe in elicitorsignaling is still unclear. Our recent studies demonstrated the involvement of vPe in elicitor signal transduction to induce stomatal closure and defense responses, including defense gene expression and hypersensitive cell death. Key words: hypersensitive cell death, elicitor, stomatal closure, pathogen-associated molecular patterns, plant innate immunity, programmed cell death activity. At least eight caspase activities have now been measured in plant extracts, which were found using caspase substrates, and various caspase inhibitors can block many forms of plant programmed cell death. 9 In the past several years, vacuolar-processing enzyme (VPE) has been determined to play important roles in plant immunity responses. In this review paper, I describe the current view on the role of VPE in plant immunity, based on our own research and recent developments in this field. The role of vacuolar processing enzymes in plant immunity Role of VPE in PCDPlant vacuoles play fundamental roles in controlling turgor pressure, molecular degradation and storage, as well as timely execution of PCD in, e.g., plant disease resistance, tissue senescence and seed development. 10,11 A ...

show abstract

Getting the Most from the Host: How Pathogens Force Plants to Cooperate in Disease

Cited by 50 publications

References 86 publications

Cryptic fungal infections: the hidden agenda of plant pathogens

Cryptic fungal infections: the hidden agenda of plant pathogens

The Lateral Organ Boundaries Domain Transcription Factor LBD20 Functions in Fusarium Wilt Susceptibility and Jasmonate Signaling in Arabidopsis

The role of vacuolar processing enzymes in plant immunity

Contact Info

Product

Resources

About