Gestational trophoblastic neoplasm of the uterus: MR assessment.

Hricak, H; Demas, Barbara E.; Braga, C.; Fisher, Madeleine R.; Winkler, Marion F.

doi:10.1148/radiology.161.1.3020607

Cited by 57 publications

(23 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It causes uterine enlargement and distension of the endometrial cavity with indistinct boundary between the endometrium and myometrium. On T1-weighted images, it is isointense or mildly hyperintense to the myometrium with areas of hemorrhage, seen as focal signal hyperintensity [23, 24]. Diffuse myometrial involvement by the tumor is seen as diffuse myometrial signal hyperintensity with obliteration of the normal zonal anatomy.…”

Section: Imaging Features Of the Uterine Diseasementioning

confidence: 99%

“…Tumor hypervascularity is also seen as prominent tortuous flow voids in the tumor and adjoining myometrium, parametrium, and adnexae on both T1 and T2-weighted images with engorgement of internal iliac and arcuate vessels with respect to the external iliac artery (Figure 9) [24]. However, the hypovascular form of PSTT has been demonstrated to be hyperintense to myometrium on both T1- and T2-weighted images with absence of prominent vascularity or flow voids and poor enhancement on postcontrast images [2].…”

Section: Imaging Features Of the Uterine Diseasementioning

confidence: 99%

“…MRI findings usually normalize at 6–9 months following effective chemotherapy. Persistent uterine vascular malformations are seen as residual tortuous and coiled vessels within a thickened myometrium [2, 20, 24]. …”

Section: Imaging Features Of the Uterine Diseasementioning

confidence: 99%

See 2 more Smart Citations

Gestational Trophoblastic Disease: A Multimodality Imaging Approach with Impact on Diagnosis and Management

Dhanda

Ramani

Thakur

2014

Radiology Research and Practice

View full text Add to dashboard Cite

Gestational trophoblastic disease is a condition of uncertain etiology, comprised of hydatiform mole (complete and partial), invasive mole, choriocarcinoma, and placental site trophoblastic tumor. It arises from abnormal proliferation of trophoblastic tissue. Early diagnosis of gestational trophoblastic disease and its potential complications is important for timely and successful management of the condition with preservation of fertility. Initial diagnosis is based on a multimodality approach: encompassing clinical features, serial quantitative β-hCG titers, and pelvic ultrasonography. Pelvic magnetic resonance imaging (MRI) is sometimes used as a problem-solving tool to assess the depth of myometrial invasion and extrauterine disease spread in equivocal and complicated cases. Chest radiography, body computed tomography (CT), and brain MRI have been recommended as investigative tools for overall disease staging. Angiography has a role in management of disease complications and metastases. Efficacy of PET (positron emission tomography) and PET/CT in the evaluation of recurrent or metastatic disease has not been adequately investigated yet. This paper discusses the imaging features of gestational trophoblastic disease on various imaging modalities and the role of different imaging techniques in the diagnosis and management of this entity.

show abstract

Section: Imaging Features Of the Uterine Diseasementioning

confidence: 99%

Section: Imaging Features Of the Uterine Diseasementioning

confidence: 99%

See 1 more Smart Citation

Gestational Trophoblastic Disease: A Multimodality Imaging Approach with Impact on Diagnosis and Management

Dhanda

Ramani

Thakur

2014

Radiology Research and Practice

View full text Add to dashboard Cite

show abstract

“…Myometrial invasion is visible as high-signal-intensity foci within the myometrium, which demonstrate enhancement on postcontrast images. Enhancing parametrial soft tissue is characteristic of local spread (40)(41)(42)(43). MR imaging can also help detect metastatic disease, particularly within the pelvic organs and lymph nodes.…”

Section: Invasive Mole and Choriocarcinomamentioning

confidence: 99%

Imaging of the Placenta: A Multimodality Pictorial Review

Elsayes¹,

Trout²,

Friedkin³

et al. 2009

RadioGraphics

186

127

View full text Add to dashboard Cite

The placenta is often overlooked in the routine evaluation of a normal gestation, receiving attention only when an abnormality is detected. Although uncommon, abnormalities of the placenta are important to recognize owing to the potential for maternal and fetal morbidity and mortality. Pathologic conditions of the placenta include placental causes of hemorrhage, gestational trophoblastic disease, retained products of conception, nontrophoblastic placental tumors, metastases, and cystic lesions. Sonography remains the imaging modality of choice for evaluation of the placenta. Magnetic resonance (MR) imaging can be of added diagnostic value when further characterization is required, particularly in the setting of invasive placental processes such as placenta accreta and gestational trophoblastic disease. Computed tomography (CT) has a limited role in the evaluation of placental disease owing to limited tissue characterization, compared with that of MR imaging, and the radiation risk to the fetus; this risk often outweighs the benefit. The primary role for CT is in the evaluation of trauma and gestational trophoblastic disease, for which it allows characterization of the primary lesion and distant metastases.

show abstract

“…MRI findings may include the following: [18,19,20,21,22] 1. Heterogeneous endometrial enlargement with several hyperintense foci that represent hydropic villi on T2-weighted imaging.…”

Section: Discussionmentioning

confidence: 99%