Gestational Hypertension and Preeclampsia

Wisner, Kirsten

doi:10.1097/nmc.0000000000000523

Cited by 29 publications

(32 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…15 Hemolysis, elevated liver enzymes and low platelets syndrome Hemolysis, elevated liver enzymes and low platelets syndrome syndrome is characterized by platelet count < 100,000 mm 3 , elevated liver function tests and microangiophatic hemolytic anemia (MHA), related to endothelial damage and coagulation activation. 13,16,17 Hemolysis, elevated liver enzymes and low platelets syndrome may result from a continuum of PE, in 10% of cases, or might occur without pre-eclamptic features, like hypertension and proteinuria, in up to 15% of cases. 12,13 Besides being more frequent in the third trimester, it can present first postpartum, in 30% of the cases.…”

Section: Gestational Thrombocytopeniamentioning

confidence: 99%

“…13,16,17 Hemolysis, elevated liver enzymes and low platelets syndrome may result from a continuum of PE, in 10% of cases, or might occur without pre-eclamptic features, like hypertension and proteinuria, in up to 15% of cases. 12,13 Besides being more frequent in the third trimester, it can present first postpartum, in 30% of the cases. 16 Clinical manifestations include upper abdominal pain, nausea, vomiting, malaise, headache and, rarely, jaundice.…”

Section: Gestational Thrombocytopeniamentioning

confidence: 99%

See 1 more Smart Citation

Update on Thrombocytopenia in Pregnancy

Subtil

Mendes

Areia

et al. 2020

Rev Bras Ginecol Obstet

View full text Add to dashboard Cite

Thrombocytopenia, defined as platelet count < 150,000 mm3, is frequently diagnosed by obstetricians since this parameter is included in routine surveillance during pregnancy, with an incidence of between 7 and 12%. Therefore, decisions regarding subsequent examination and management are primordial. While most of the cases are due to physiological changes, as gestational thrombocytopenia, other causes can be related to severe conditions that can lead to fetal or maternal death. Differentiating these conditions might be challenging: they can be pregnancy-specific (pre-eclampsia/HELLP syndrome [hemolysis, elevated liver enzymes, low platelets]), or not (immune thrombocytopenia purpura, thrombotic thrombocytopenic purpura or hemolytic uremic syndrome). Understanding the mechanisms and recognition of symptoms and signs is essential to decide an adequate line of investigation. The severity of thrombocytopenia, its etiology and gestational age dictates different treatment regimens.

show abstract

Section: Gestational Thrombocytopeniamentioning

confidence: 99%

Section: Gestational Thrombocytopeniamentioning

confidence: 99%

Update on Thrombocytopenia in Pregnancy

Subtil

Mendes

Areia

et al. 2020

Rev Bras Ginecol Obstet

View full text Add to dashboard Cite

show abstract

“…Several mechanisms of disease have been proposed, such as chronic uteroplacentar ischemia, immune maladaptation, very-lowdensity lipoprotein toxicity, genetic imprinting, increased trophoblast apoptosis or necrosis, an exaggerated maternal inflammatory response, and an imbalance of angiogenic factors. 6 relação entre hiperparatiroidismo primário e pré-eclâmpsia. Apresenta-se um caso de uma grávida de 27 semanas com pré-eclâmpsia com critérios de gravidade, o que obrigou ao término da gravidez por cesariana.…”

Section: Discussionunclassified

Preeclampsia as an Inaugural Manifestation of Primary Hyperparathyroidism: A Case Report

Leite

Ormonde

et al. 2020

Rev Bras Ginecol Obstet

View full text Add to dashboard Cite

Primary hyperparathyroidism is an endocrine disorder characterized by hypercalcemia and elevated or inappropriately normal levels of parathyroid hormone. The diagnosis is based on a biochemical evaluation, and a neck ultrasound is the first choice during pregnancy to access the parathyroid glands. Manifestations during pregnancy are rare and can be present with life-threatening complications, so the diagnosis is challenging. The conservative treatment is limited, and there is not enough data about its safety and efficacy during pregnancy. Surgery is the only curative treatment, and a parathyroidectomy performed during the second or third trimesters is considered safe. Recently, some authors suggested an association between primary hyperparathyroidism and preeclampsia. We describe a case of preeclampsia with severe features at 27 weeks of gestational age. The severity of the preeclampsia motivated an early termination of the pregnancy by cesarean section. During the postpartum period, the patient presented life-threatening complications, such as severe hypercalcemia and acute pancreatitis. An ultrasound exam found two parathyroid nodules, suggestive of parathyroid adenomas. The patient recovered after the pharmacological correction of the calcemia levels.

show abstract

“…16 Acorde a las guías americanas de obstetricia (American College of Obstetrics & Gynecology) los trastornos hipertensivos del embarazo se clasifican según se señalan en la tabla 2. 17 La relevancia a futuro de estos trastornos radica en su relación establecida con el riesgo cardiovascular y su impacto en salud y costos. 18 Desde el estudio Framingham de 1948 se viene reconociendo la importancia de la hipertensión como un factor crucial en el desarrollo de enfermedades cardiovasculares.…”

Section: Trastornos Hipertensivos En El Embarazo Y Riesgo Cardiovascularunclassified

“…Tanto las guías de la AHA como la ACOG recomiendan indistintamente el uso de alfa y beta bloqueadores mixtos o bloqueante de canales de calcio (nifedipino). 17 A falta de un score objetivo que permita evaluar el riesgo a 10 años, se han llevado a cabo estudios que miden la incidencia de desenlaces cardiovasculares antes y después de 10 años de seguimiento en pacientes con diagnóstico de preeclampsia/hipertensión gestacional, encontrándose lo siguiente (Tabla 4). [30][31][32][33]…”

Section: Trastornos Hipertensivos En El Embarazo Y Riesgo Cardiovascularunclassified

Enfermedades cardio-metabólicas en el embarazo: Revisión sobre diagnóstico, tratamiento y proyección del riesgo cardiovascular a largo plazo

Manzur

Corrales-Santander

Pacheco-Ayos

et al. 2020

Rev. chil. obstet. ginecol.

View full text Add to dashboard Cite

Las enfermedades cardiovasculares representan la mayor causa de morbimortalidad a nivel mundial. Si bien presenta un descenso en la población general, en las mujeres tiende a mantenerse estable la prevalencia de enfermedad coronaria. Varios factores propios de la mujer predisponen a que esto ocurra, incluyendo el embarazo, mediado tanto por los cambios hematológicos y cardiovasculares característicos de la gestación; como por patologías asociadas, principalmente trastornos hipertensivos del embarazo y diabetes gestacional. Su presencia se ha asociado fuertemente a la aparición a futuro de otras patologías de alto riesgo cardiovascular como hipertensión crónica, dislipidemia y diabetes mellitus. Dado el impacto que esto representa, se hace imperante la identificación de grupos de alto riesgo y la implementación de medidas preventivas, así como de diagnóstico precoz y tratamientos adecuados con el fin de disminuir complicaciones materno-fetales en las etapas perinatal y posparto.

show abstract

Gestational Hypertension and Preeclampsia

Cited by 29 publications

References 0 publications

Update on Thrombocytopenia in Pregnancy

Update on Thrombocytopenia in Pregnancy

Preeclampsia as an Inaugural Manifestation of Primary Hyperparathyroidism: A Case Report

Enfermedades cardio-metabólicas en el embarazo: Revisión sobre diagnóstico, tratamiento y proyección del riesgo cardiovascular a largo plazo

Contact Info

Product

Resources

About