Gestational choriocarcinoma arising from a cornual ectopic pregnancy: a case report and review of the literature

Rotas, Michael; Khulpateea, Neekianund; Binder, David

doi:10.1007/s00404-007-0394-5

Cited by 28 publications

(20 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Choriocarcinoma occurring at the site of ectopic pregnancy in the tube was reported by Kucukozkan et al and by Bakri et al 1,2 In a study of 162 patients with gestational trophoblastic disease only 4 had the disease at the ectopic site. 3 The presenting signs and symptoms in all cases were similar to those classically outlined for ectopic pregnancy and those that were seen in the present case. The time of presentation of choriocarcinoma varies.…”

Section: Discussionsupporting

confidence: 74%

Gestational Choriocarcinoma Arising from an Ectopic Pregnancy

Dahiya

Duhan

Singh

et al. 2010

Journal of Gynecologic Surgery

View full text Add to dashboard Cite

Background: Gestational choriocarcinoma associated with ectopic pregnancy is an extremely rare event. This article reports a case of a choriocarcinoma arising from an ectopic pregnancy. Case: The patient was a 30-year-old woman who was admitted with pain and amenorrhoea. Ultrasonography revealed a heterogeneous mass, 5.8Â6.3 cm, in the left adnexa. At emergency laparotomy, a left salpingectomy was performed. The patient did not come for follow-up. She returned after 10 weeks with pain in her abdomen, vomiting, and a pelvic mass. Relaparotomy was done. On separating the adhesions, an organised blood clot of *700 cc, along with some tissue, were removed from the pouch of Douglas. Active bleeding started from the raw surface; this bleeding could not be controlled. Hence, the bilateral iliac artery and ovarian artery were ligated. Histopathologic investigation revealed choriocarcinoma. Conclusions: A choriocarcinoma is a malignant tumor that arises from the epithelium of the chorionic villi. Associated with ectopic pregnancy, this kind of tumor is extremely rare and is generally very aggressive. In 75% of cases, it items from distant metastasis; therefore, a histologic examination of the tubes must be performed in all ectopic pregnancies. ( J GYNECOL SURG 26:273)

show abstract

Section: Discussionsupporting

confidence: 74%

Gestational Choriocarcinoma Arising from an Ectopic Pregnancy

Dahiya

Duhan

Singh

et al. 2010

Journal of Gynecologic Surgery

View full text Add to dashboard Cite

show abstract

“…However, its use in gestational choriocarcinoma diagnosis remains controversial, with only several cases reported in the literature 5,6 . The main reason for its limited use is the fear of heavy blood loss and distant metastasis.…”

Section: Discussionmentioning

confidence: 99%

Prognosis of gestational choriocarcinoma diagnosed incidentally during laparoscopy for a presumed cornual pregnancy: a report of five cases

Liu¹,

Fan²,

Feng³

et al. 2017

Cancer Biology & Medicine

View full text Add to dashboard Cite

The clinical presentations of gestational choriocarcinoma vary markedly, and a misdiagnosis could be made in atypical patients if simply relying on clinical features. Laparoscopic resection of uterine mass lesion is rarely used in gestational choriocarcinoma diagnosis because of the fear of heavy blood loss and distant metastasis. Five patients who were preoperatively diagnosed as having cornual pregnancy underwent laparoscopic resection of mass lesion and then proved to have gestational choriocarcinoma based on pathological examinations. Chemotherapy was started within two days after surgery, and the rate of complete remission was 100%. The mean follow-up time was 29.8±19.1 months, and no patient showed signs of relapse. Laparoscopic resection of uterine mass followed by timely postoperative chemotherapy may be an effective and safe way to obtain pathologic results in patients with suspected gestational choriocarcinoma.

show abstract

“…The definitive diagnosis can be made as often as in the postoperative period histopathologically. 13 Treatment can be made with laparoscopy in 50% of cases, rest requires laparotomy.…”

Section: Discussionmentioning

confidence: 99%