Gestational Choriocarcinoma Arising from an Ectopic Pregnancy

Abstract

Background: Gestational choriocarcinoma associated with ectopic pregnancy is an extremely rare event. This article reports a case of a choriocarcinoma arising from an ectopic pregnancy. Case: The patient was a 30-year-old woman who was admitted with pain and amenorrhoea. Ultrasonography revealed a heterogeneous mass, 5.8Â6.3 cm, in the left adnexa. At emergency laparotomy, a left salpingectomy was performed. The patient did not come for follow-up. She returned after 10 weeks with pain in her abdomen, vomiting, and a pelvic mass. Relaparotomy was done. On separating the adhesions, an organised blood clot of *700 cc, along with some tissue, were removed from the pouch of Douglas. Active bleeding started from the raw surface; this bleeding could not be controlled. Hence, the bilateral iliac artery and ovarian artery were ligated. Histopathologic investigation revealed choriocarcinoma. Conclusions: A choriocarcinoma is a malignant tumor that arises from the epithelium of the chorionic villi. Associated with ectopic pregnancy, this kind of tumor is extremely rare and is generally very aggressive. In 75% of cases, it items from distant metastasis; therefore, a histologic examination of the tubes must be performed in all ectopic pregnancies. ( J GYNECOL SURG 26:273)

Coriocarcinoma primario de trompa uterina: reporte de dos casos

“…El coriocarcinoma primario de trompa se puede originar de la malignización de un embarazo ectópico o una mola hidatiforme ectópica tubárica, o de novo sin embarazo previo (15)(16)(17) . Si fuera de tipo gestacional, su origen debió producirse en el trofoblasto de un estadio embrionario muy temprano y con la muerte precoz del embrión; mucho más temprano que los coriocarcinomas intraplacentarios.…”