Georg Christoph Lichtenberg in Engeland

Regulatory relationship between PTSM and PTSG in Escherichia coli

“…Recently, Scholte and Postma [7] have shown that in Salmonella typhimurium, non-metabolizable analogs specific to enzyme II glc (PTSG) inhibit the activity of PTSM as measured by the uptake of labeled mannose and by the oxidation of mannose. This inhibition is not due to competition for binding to enzyme II man as inhibition is absent in a S. typhimurium ptsG mutant which lacks enzyme II g~c but possesses functional enzyme II'a".…”

“…This inhibition is not due to competition for binding to enzyme II man as inhibition is absent in a S. typhimurium ptsG mutant which lacks enzyme II g~c but possesses functional enzyme II'a". Scholte and Postma [7] predict that in wild-type S. typhimurium glucose is used preferentially through PTSG.…”