Geometrical-Optics Approximation for the Simulation of Light Scattering by Single-Nuclear Cell

Abstract

According to the morphology of the single-nuclear cell, the eccentric-sphere (ES) model is proposed. The analytic expressions of amplitude function and phase function are revised base on the geometrical-optics approximation (GOA).The intensity distributing and phase distributing of the single-nuclear cell are also simulated by numerical calculation. The incident light orientation and the size of the nuclear on the impact of the backscattering have been discussed. After the analysis, we find that the model and the theory are much closer to the experimental fact compared with the single sphere model. These promote perfecting of the revised theory for inspection of real cell and provide a theory foundation for improving the measuring technique and identification technique of cells.

On the electromagnetic scattering of arbitrary shaped beams by arbitrary shaped particles: A review

“…Rancourt-Grenier et al [196] studied the dynamic deformation of a soft particle in dual-trap optical tweezers using ray tracing, together with GLMT (under the name "T-matrix approach") and FDTD (see below for the meaning of FDTD), see also [197] using the same methods to study the dynamic deformation of a red blood cell in a dual-trap optical tweeezers. Bu and Wang dealt with the geometrical optics approximation for the simulation of light scattering by single-nuclear cells, using an eccentric-sphere model [198]. Zhou et al carried out calculations of optical forces on an triaxial ellipsoid in an optical trap with spherical aberration using vectorial ray tracing [199].…”

Latest achievements in generalized Lorenz‐Mie theories: A commented reference database

“… dealt with the study of dynamic deformation of soft particles in a dual‐trap optical tweezers. Bu and Wang dealt with the simulation of light scattering by single‐nuclear cells, using an eccentric‐sphere model. Sadeghi et al .…”