The northern margin of the North China Craton (NCC) contains widespread Permian magmatic rocks, but the origin of these rocks remains controversial. This uncertainty hampers us from better understanding of tectonic framework and evolution of the eastern Paleo‐Asian Ocean, particularly with respect to its final‐stage subduction and closure time. To address these questions, this study presents petrological, zircon U‐Pb geochronological, whole‐rock geochemical and in situ zircon Hf isotopic data for these Permian mafic intrusions in the northern margin of the NCC. Precise zircon U‐Pb dating results indicate that these mafic intrusions were emplaced in the Middle Permian (ca. 260 Ma). Geochemically, the studied mafic intrusions have high MgO and transition metals element contents, with high Mg# values, indicating a mantle origin. These mafic intrusions are characterized by enrichments in large ion lithophile elements (LILEs; e.g., Rb, Ba, and K) and light rare earth elements (LREEs), and depletions in high field strength elements (HFSEs; e.g., Nb, Ta, and Ti) and heavy rare earth elements (HREEs), indicating that they were formed in a subduction‐related setting. These geochemical features, together with zircon ∊Hf(t) values (–1.1 to +11.2), indicate that their parental magmas were derived from partial melting of heterogeneous mantle wedge metasomatized by subduction‐related fluids, with the contributions of slab sediments. The studied mafic intrusions also show wide range of major and trace elements contents, and variable Mg# values, Eu and Sr anomalies, suggesting that their parental magmas had undergone variable degrees of fractional crystallization. Together with the E–W trending Permian continental arc along the northern margin of the NCC, we confirm that the generation of the Middle Permian mafic intrusions was related to southward subduction of the Paleo‐Asian oceanic lithosphere beneath the NCC and the Paleo‐Asian Ocean had not closed prior to the Middle Permian.