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The Mingshui–Jilasitai–Suolun area, located in the central part of the Great Xing’an Range, is characterized by large volumes of alkali feldspar granites. However, the formation time and tectonic setting of these rocks remains controversial owing to a lack of precise geochronological and detailed geochemical data. In this paper, we report new SIMS U–Pb zircon ages and mineralogical, petrographical and geochemical data for Lower Cretaceous alkali feldspar granites from the Mingshui–Jilasitai–Suolun area. The SIMS zircon dating results indicate that these granites formed at 133.6–135.9 Ma. The mineralogical, petrographical and geochemical data show that these granitic rocks belong to highly fractionated I-type granites. Combined with the regional geology data, we propose that the formation of the Lower Cretaceous alkali feldspar granitic rocks was related to an extension induced by delamination of the lithosphere that arose from subduction of the Palaeo-Pacific plate.