Genotypically unique Babesia spp. isolated from reindeer (Rangifer tarandus tarandus) in the United States

Pj, Holman; Pk, Swift; Re, Frey; Bennett, Jason; Cruz, D; Gg, Wagner

doi:10.1007/s00436-001-0576-1

Cited by 21 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Babesia capreoli is another species that is prevalent in free-living roe deer and sika deer on the European continent [ 11 , 14 , 15 ]. In America, the main pathogen of deer babesiosis is Babesia odocoilei, which has been detected in roe deer, reindeer and elk [ 16 , 17 ]. Some novel Babesia spp.…”

Section: Introductionmentioning

confidence: 99%

Molecular detection and identification of piroplasms in sika deer (Cervus nippon) from Jilin Province, China

et al. 2016

View full text Add to dashboard Cite

BackgroundPiroplasmosis is an important disease of domestic animals and wildlife and is caused by organisms from the genera Theileria and Babesia. Wildlife such as sika deer play an important role as reservoir hosts for several species of Theileria and Babesia. Using blood samples collected from sika deer, we investigated the epidemiology of Theileria spp. and Babesia spp. in sika deer from Jilin Province in China and identified those species that cause pathogenic infections in sika deer.MethodsSixty-eight blood samples of sika deer were collected from three areas of the Jilin Province in Northeast China. Genomic DNA was extracted, and the V4 hypervariable region of the 18S rRNA of the piroplasms was amplified using the nested PCR method. The selected positive samples were sequenced to identify species of Babesia and Theileria.ResultsPCR detection revealed that 24 samples were positive for Theileria and Babesia spp. (35.29 %, 95 % CI = 11.8-46.8). After alignment, a sequenced fragment for Theileria cervi was found to be the most prevalent from the obtained samples (22.06 %, 95 % CI = 11.8-49.6). Six sika deer samples were identified as being infected with a Theileria sp. that was similar to a Theileria sp. found from spotted deer in India. In addition to the results above, for the first time, we identified T. annulata infection from one sample of sika deer and Babesia sp. from two samples, which showed high identity with Babesia motasi found in sheep from China.ConclusionThe present study offers new data on the pathogens of piroplasmosis in sika deer in northeastern China. For the first time, sika deer was confirmed as a reservoir host for the T. annulata of cattle and the B. motasi of sheep, which was found in China.

show abstract

Section: Introductionmentioning

confidence: 99%

Molecular detection and identification of piroplasms in sika deer (Cervus nippon) from Jilin Province, China

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Fatal babesiosis in domestic reindeer was initially described in Russia in the early 1900s, but additional cases have been identified in other countries including the US . Two genotypically unique Babesia spp (a B odocoilei ‐like organism and a larger Babesia organism similar to B caballi ) were isolated from clinically normal reindeer in California . Other Babesia spp cause disease in reindeer.…”

Section: Discussionmentioning

confidence: 99%

Theileriosis in a reindeer (Rangifer tarandus tarandus) associated with a potentially novel Theileria sp

Garner

Holman

Berent

2012

Veterinary Clinical Pathol

View full text Add to dashboard Cite

A 5-year-old male neutered reindeer (Rangifer tarandus tarandus) from Missouri was presented with a 3-week history of anorexia, respiratory distress, lethargy, and weight loss. Blood smear review revealed that a small percentage of RBCs contained small (1-2 μm in length) pleomorphic piroplasms (signet ring, rod- or pear-shaped, and elongate forms) with an eccentric magenta nucleus and basophilic cytoplasm. Nested PCR to specifically amplify a portion of the piroplasm small subunit ribosomal RNA (SSU rRNA) gene was performed on DNA extracted from an EDTA specimen of whole blood. Subsequent sequence analyses showed similarity between the reindeer hemoparasite and Theileria spp SSU rRNA gene sequences in the GenBank database, with highest similarity to those of a Theileria sp in a White-tailed deer from North Texas (AY735132, AY735133). The reindeer and North Texas Theileria sp are genetically distinct from, albeit closely related to, the White-tailed deer Theileria sp (subsequently referred to as T cervi). To the authors' knowledge, this is the first identification of Theileria of this genotype in a reindeer. Historically, T tarandirangiferis infection was found with associated mortality in reindeer in Russia, but reports predate molecular characterization. Hence, the relationship of T tarandirangiferis with either T cervi or this agent remains unknown. T cervi is not typically pathogenic in White-tailed deer in the US unless the animal is immune-compromised by stress or disease; however, mortality from T cervi infection in reindeer has been reported.

show abstract

“…B. odocoilei , which is transmitted by I. scapularis , primarily infects white-tailed deer in the United States (5). Cases of fatal babesiosis were described in 2 other species of cervids, namely a zoo-housed caribou ( Rangifer tarandus caribou ) and an elk ( C. elaphus elaphus ) (9). Therefore, we tested 2 species of cervids from Slovenia as potential reservoir hosts of EU1.…”

Section: Discussionmentioning

confidence: 99%

Cervids as Babesiae Hosts, Slovenia

Duh

Petrovec

Bidovec³

et al. 2005

Emerg. Infect. Dis.

View full text Add to dashboard Cite

We describe cervids as potential reservoir hosts of Babesia EU1 and B. divergens . Both babesial parasites were found in roe deer. Sequence analysis of 18S rRNA showed 99.7% identity of roe deer Babesia EU1 with the human EU1 strain. B. divergens detected in cervids was 99.6% identical to bovine B. divergens .

show abstract

Genotypically unique Babesia spp. isolated from reindeer (Rangifer tarandus tarandus) in the United States

Cited by 21 publications

References 16 publications

Molecular detection and identification of piroplasms in sika deer (Cervus nippon) from Jilin Province, China

Molecular detection and identification of piroplasms in sika deer (Cervus nippon) from Jilin Province, China

Theileriosis in a reindeer (Rangifer tarandus tarandus) associated with a potentially novel Theileria sp

Cervids as Babesiae Hosts, Slovenia

Contact Info

Product

Resources

About