Genotoxicity and toxicity assay of water sampled from a radium production industry storage cell territory by means of Allium-test

Evseeva, T.; Гераськин, С. А.; Шуктомова, И. И.

doi:10.1016/s0265-931x(03)00054-7

Cited by 61 publications

(41 citation statements)

References 7 publications

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“…A combination of biological and pollutant chemical control methods allow identifying the major sources of risk, which require a continuous monitoring. Our previous [2] and described here data suggest that combined exposure of metal ions and radionuclides on the various biota species with the dose below permissible exposure limits for human may cause substantial biological effects, in part due to synergic response.…”

Section: Resultsmentioning

confidence: 60%

“…Nevertheless, the overall HNRs concentrations in all samples were found not to exceed the radioactivity concentration guides. Zn and Mn levels in all samples analysed as well as Ca from Brook II exceeded the maximum permissible concentrations for natural reservoirs [2].…”

Section: The Water Bodies Contamination Assessment At the Radium Prodmentioning

confidence: 79%

“…The developing roots were maintained at 22 ± 2° C. When the roots began to grow (up to 0.2 cm length), the bulbs were plunged into the water samples to be studied. Control samples remained in distilled water (for more details, see [2]). Distilled water was chosen for the bulb germination on the basis of our previous experiments where the reaction of Allium cepa root tip cells to environmental pollutants were showed to be regardless of whether these pollutants were supplied in a Knop medium or distilled water.…”

Section: Allium-testmentioning

confidence: 99%

“…Atomic absorption method was used for measuring Ca and Mg content (RD 52.04.186-89) and Cu, Pb, Cd, Zn, Mn, Ni (RD 52.24.377-95). Radiochemical analysis for assessing RNs contents in water samples was performed in the Radiochemical laboratory of the Institute of Biology of Komi Scientific Center accredited within the Accrediting System for analytical laboratories in Russia (for more details, see [2]). The results were subjected to statistical analysis by means of generally accepted methods [5].…”

Section: Determination Of Heavy Metals (Hms) and Radionuclides (Rns) mentioning

confidence: 99%

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Genotoxicity and cytotoxicity assay of water sampled from natural reservoirs with contrast level of radioactive and chemical contamination

et al. 2005

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Abstract. Comparative analysis of water from natural reservoirs located near a place of the underground nuclear explosion with rock outburst (Perm region) and the radium production industry storage cell (Komi Republic) with contrast levels of radioactive and chemical contamination was performed for the first time using bioindication and chemical analysis. Bioindication was carried out with anaphase-telophase chromosome aberration assay on A. schoenoprasum L. meristematic root tip cells. Even at very low levels of specific activity, both natural ( 238 U, 232 Th, 226 Ra, 210 Po, 210 Pb) and artificial ( 90 Sr, 137 Cs, 230,240 Pu) radionuclides contribute significantly (59-91 %) to an induction of genotoxic and toxic effects. The chemical factors strengthened or weakened the cytotoxicity effects and may modify a formation of certain type of chromosome disturbances. Our results clearly indicate that combined exposure to metal ions and radionuclides at levels officially adopted as permissible for humans may act synergistically and result in significant damage to different biota species.

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Section: Resultsmentioning

confidence: 60%

Section: The Water Bodies Contamination Assessment At the Radium Prodmentioning

confidence: 79%

Section: Allium-testmentioning

confidence: 99%

Section: Determination Of Heavy Metals (Hms) and Radionuclides (Rns) mentioning

confidence: 99%

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Genotoxicity and cytotoxicity assay of water sampled from natural reservoirs with contrast level of radioactive and chemical contamination

et al. 2005

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“…On the other hand, MIs above those of the negative control are result of the induction of increased cell division, which may characterize an event detrimental to cells, leading to uncontrolled proliferation and even tumor formation (Hoshina et al, 2002). The increased cell proliferation activity can be the consequence of a reduction of the time necessary for DNA repair (Evseeva et al, 2003).…”

Section: Resultsmentioning

confidence: 99%

Evaluation of genotoxic and mutagenic effects of aqueous extract from aerial parts of Linaria genistifolia subsp. genistifolia

Liman¹,

Gökçe²,

Akyıl³

et al. 2012

Rev. bras. farmacogn.

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Genotoxic and mutagenic effects of aqueous extract from aerial parts Linaria genistifolia (L.) Mill. subsp. genistifolia, Plantaginaceae (Lg-ext) were investigated by using both Allium cepa root meristematic cells and bacterial reverse mutation assay in Salmonella typhimurium TA98 and TA100 with or without metabolic activation system (S9), respectively. In Allium root growth inhibition test, EC50 value was determined approximately 15 g/L and 0.5xEC50, EC50 and 2xEC50 concentrations of Lg-ext were introduced to onion tuber roots and distilled water and methyl methane sulfonate (MMS, 10 ppm) used as a negative and positive control, respectively. The characteristic effect caused by tested preparations was an increase of mitotic index (MI) in 7.5 g/L and 15 g/L (except 24 and 96 h) and simultaneous decrease of MI in 30 g/L and in MMS. While stickiness, bridges, chromosome laggards and disturbed anaphase-telophase were observed in anaphase-telophase cells, c-metaphase, pro-metaphase, polyploidy and binuclear cells were observed in other cells. Lg-ext was not found to be mutagenic on S. typhimurium TA 98 and TA100 with or without S9. The results were also analyzed statistically by using SPSS for Windows, and Duncan's multiple range tests were performed respectively. These results indicate that Lg-ext exhibits genotoxic activity in A. cepa root meristematic cells but not mutagenic activity in Ames test system.

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Genetic Ecotoxicology and Risk Assessment: An Overview

Goncharova

NATO Security Through Science Series

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Genotoxicity and toxicity assay of water sampled from a radium production industry storage cell territory by means of Allium-test

Cited by 61 publications

References 7 publications

Genotoxicity and cytotoxicity assay of water sampled from natural reservoirs with contrast level of radioactive and chemical contamination

Genotoxicity and cytotoxicity assay of water sampled from natural reservoirs with contrast level of radioactive and chemical contamination

Evaluation of genotoxic and mutagenic effects of aqueous extract from aerial parts of Linaria genistifolia subsp. genistifolia

Genetic Ecotoxicology and Risk Assessment: An Overview

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