Genome Sequence of Vibrio parahaemolyticus VP103 Strain Isolated from Shrimp in Malaysia

Letchumanan, Vengadesh; Ser, Hooi‐Leng; Chan, Kok‐Gan; Goh, Bey Hing; Lee, Learn‐Han

doi:10.3389/fmicb.2016.01496

Cited by 20 publications

(17 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[5,83,84] , Vibrio sp. [85][86][87][88][89][90][91] , and Salmonella sp. [92][93][94][95][96] that commonly affect human and animal health.…”

Section: Resultsmentioning

confidence: 99%

Decoding the mystery of how bacteria “talk”: Among Gram-negative microorganisms

Tan¹,

Law²,

Letchumanan³

et al. 2019

Prog Micobes Mol Biol

Self Cite

View full text Add to dashboard Cite

To date, microbial diversity is still the least well understood component of biodiversity. Bacteria are the most abundant microorganisms where most species are often found ubiquitous. Microorganisms such as bacteria are diverse in their impacts such as in spreading of infectious diseases or play a valuable role in biotechnological purposes. Hence, it is interesting to gain a look upon the ways where bacteria regulate their daily processes in the environment. Bacteria communicate with each other through extracellular signalling molecules or also known as autoinducers (AIs) that are produced, detected and show response. This process is termed as quorum sensing (QS) which indicates that bacteria do communicate in order to perform various physiological activities. QS enable bacteria to have the advantages that are unattainable as individual bacterial cell. This review emphases on the characteristics of quorum sensing (QS) and its benefits in understanding different kind of bacterial QS-dependent activities. This fundamental insight from QS system will enable us to manage bacterial activities by targeting their communication circuit.

show abstract

“…[5,83,84] , Vibrio sp. [85][86][87][88][89][90][91] , and Salmonella sp. [92][93][94][95][96] that commonly affect human and animal health.…”

Section: Resultsmentioning

confidence: 99%

Decoding the mystery of how bacteria “talk”: Among Gram-negative microorganisms

Tan¹,

Law²,

Letchumanan³

et al. 2019

Prog Micobes Mol Biol

Self Cite

View full text Add to dashboard Cite

show abstract

“…This is a worrying scenario as the antibiotic resistant profile exhibited by the strain is among the recommended antibiotics agents used in treatment if Vibrio sp. infection [35][36][37] . The Vibrio sp.…”

Section: Introductionmentioning

confidence: 99%

Genome sequence of Vibrio sp. OULL4 isolated from shellfish

Letchumanan¹,

Tan²,

Yin³

et al. 2020

Prog Micobes Mol Biol

Self Cite

View full text Add to dashboard Cite

The members of Vibrionaceae family are Gram-negative bacterium are ubiquitous in marine and estuarine environments. This diverse group of bacteria include many pathogenic strains that potentially cause infection to humanand aquaculture animals. Vibrio cholerae, Vibrio parahaemolyticus and Vibrio vulnificus are among the few recognized as a major, worldwide cause gastroenteritis, particularly in countries where seafood consumption is high. The control of these vibrios has been a hurdle due to the rising numbers of antibiotic resistant strains in the environments. We report the genome sequence of Vibrio sp. OULL4 isolated from shellfish. The availability of this genome sequence will facilitate the study of its antimicrobial traits, as well as add our knowledge of Vibrio sp. diversity and evolution.

show abstract

“…The mortality rate of infected fishes could be up to 90%, thus, potentially causing great damages to aquaculture. V. parahaemolyticus contains several hemolysin toxins, namely thermolabile hemolysin (TLH), thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH) which are encoded by the tlh, tdh, and trh genes, respectively, in chromosome II (Ahn et al, 2016;Kalburge et al, 2014;Kim et al, 2016;Letchumanan et al, 2016). These hemolysins are considered as important virulence factors of V. parahaemolyticus, as they caused a variety of pathogenic consequences, including hemolytic activity, cytotoxicity, cardiotoxicity, and enterotoxicity.…”

Section: Introductionmentioning

confidence: 99%

Development of attenuated Vibrio parahaemolyticus mutant strains as potential live vaccines

Huyen

Viết

Tam

et al. 2020

APJMBB

View full text Add to dashboard Cite

Vibrio parahaemolyticus is a pathogenic Gram-negative bacterium that commonly infects numerous species of marine fishes. In this study, we obtained eight attenuated mutant strains by the selection of rifampicin-resistant V. parahaemolyticus from three wild-type strains. Among eight selected strains, four strains (L4650, A650, L4200 and A400) were widely attenuated by virulence analysis. Sequences of two genes, tlh and toxR, that related to virulence were analyzed. The results showed that seven attenuated strains were different in sequences of the tlh gene while there was no difference in sequence of toxR gene in comparison with that of wild-type strains. Three attenuated strains (L4650, L4200 and A650) had the nucleotide changes in tlh gene that resulted to the changes in the size of deduced amino acid sequences. In addition, rpoB gene coding for -subunit of RNA polymerase that related to Rifampicin resistance was analyzed for all selected strains. Two strains (A650 and L4650) had the nucleotide changes in ropB sequence. To assess the potential use of the L4650 strain as a live attenuated vaccine, the groupers (Epinephelus coioides) were intraperitoneally injected with the L4650 strain and later challenged with the virulent wild-type strain at three different doses. Results showed the protection for L4650 strain vaccinated-fish produced relatively earlier than usual at 15 days post-vaccination with relative percent survival (RPS) values from 96.91-100%. At 60 days post-vaccination, the RPS values of vaccinated fish were 96.27-100%. Our results suggest the L4650 strain could become a potential vaccine candidate against V. parahaemolyticus for future studies.

show abstract

Genome Sequence of Vibrio parahaemolyticus VP103 Strain Isolated from Shrimp in Malaysia

Cited by 20 publications

References 26 publications

Decoding the mystery of how bacteria “talk”: Among Gram-negative microorganisms

Decoding the mystery of how bacteria “talk”: Among Gram-negative microorganisms

Genome sequence of Vibrio sp. OULL4 isolated from shellfish

Development of attenuated Vibrio parahaemolyticus mutant strains as potential live vaccines

Contact Info

Product

Resources

About