Genome deletion and insertion polymorphisms (DIPs) in the Hungarian population

Kis, Zoltán; Zalán, Andrea; Völgyi, Antónia; Kozma, Zsolt; Domján, L; Pamjav, Horolma

doi:10.1016/j.fsigen.2011.09.004

Cited by 34 publications

(22 citation statements)

References 5 publications

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“…D A distances between the 16 groups with each other based on allelic frequencies of the 30 InDel loci were shown in Table 2. Short genetic distances were found between the Tujia group and Shanghai Han17, Guangdong Han18, South Korean23, Beijing Han9, Xibe10, She17, Tibetan9, and Yi16 groups; and further distances were observed between the Tujia group and Chinese Kazak9, Uigur9 groups; whereas the larger distances were estimated with Uruguayan24, Dane25, Central Spanish26, Basque26, and Hungarian populations27. Pairwise populations had small genetic distances, which indicated that they had close genetic relationships or shared a recent common ancestor.…”

Section: Resultsmentioning

confidence: 90%

A 30-InDel Assay for Genetic Variation and Population Structure Analysis of Chinese Tujia Group

Shen

Zhu

Yao

et al. 2016

Sci Rep

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In the present study, thirty autosomal insertion and deletion polymorphic loci were simultaneously amplified and genotyped in a multiplex system, and their allelic frequencies as well as several forensic parameters were obtained in a sample of 236 unrelated healthy Tujia individuals. All the loci were in Hardy-Weinberg equilibrium after applying a Bonferroni correction and all pair-wise loci showed no significant linkage disequilibrium. These loci were observed to be relatively informative and discriminating, quite efficient for forensic applications. Allelic frequencies of 30 loci were compared between the Tujia group and other reference populations, and the results of analysis of molecular variance indicated the Tujia group showed the least significant differences with the Shanghai Han at one locus, and the most with Central Spanish population at 22 loci. We analyzed the population genetic structure by the principal component analysis, the clustering of STRUCTURE program and a Neighbor-Joining tree, and then evaluated the genetic relationships among Tujia and other 15 populations.

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Section: Resultsmentioning

confidence: 90%

A 30-InDel Assay for Genetic Variation and Population Structure Analysis of Chinese Tujia Group

Shen

Zhu

Yao

et al. 2016

Sci Rep

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“…The result was shown in Table . The smaller distances were observed with six East Asian groups including South Korean , Tibetan , Guangdong Han , Shanghai Han , Beijing Han , and She , while the larger distances were observed with five European groups including Dane , Basque, Central Spanish , Uruguayan , and Hungarian . Moreover, the D A distances were used to construct the phylogenetic tree using neighbor‐joining method (shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

Forensic evaluation and population genetic study of 30 insertion/deletion polymorphisms in a Chinese Yi group

et al. 2015

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Insertion/deletion polymorphisms have become a research hot spot in forensic science due to their tremendous potential in recent years. In the present study, we investigated 30 indel loci in a Chinese Yi ethnic group. The allele frequencies of the short allele of the 30 indel loci were in the range of 0.1025-0.9221. The power of discrimination values were observed ranging from to 0.2630 (HLD111 locus) to 0.6607 (HLD70 locus) and probability of exclusion values ranged from 0.0189 (HLD111 locus) to 0.2343 (HLD56 locus). The combined power of discrimination and power of exclusion for 30 loci in the studied Yi group were 0.99999999995713 and 0.97746, respectively, which showed tremendous potential for forensic personal identification in the Yi group. Moreover, the DA distances, phylogenetic tree, principal component analysis, and cluster analysis showed the Yi group had close genetic relationships with the Tibetan, South Korean, Chinese Han, and She groups.

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“…Thus, the great evolutionary phenomenon of the African population was due to the expansion of Bantu tribes along two main different regions -East, where Mozambique is included, and West of Africa where Angola and Guinea-Bissau are included [23,24].…”

Section: Discussionmentioning

confidence: 99%

“…The Investigator® DIPplex kit (Qiagen, Hilden, Germany) has already been employed in some population studies, specially in populations of European, American and Asian origin [8][9][10]12,[16][17][18][19][20][21][22][23][24]. Demonstrating high discrimination power and high power of exclusion, has shown to be proper for forensic cases, specially, in individual identification that require analysis of degraded samples.…”

Section: Introductionmentioning

confidence: 99%

Study of InDel genetic markers with forensic and ancestry informative interest in PALOP’s immigrant populations in Lisboa

et al. 2016

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Genome deletion and insertion polymorphisms (DIPs) in the Hungarian population

Cited by 34 publications

References 5 publications

A 30-InDel Assay for Genetic Variation and Population Structure Analysis of Chinese Tujia Group

A 30-InDel Assay for Genetic Variation and Population Structure Analysis of Chinese Tujia Group

Forensic evaluation and population genetic study of 30 insertion/deletion polymorphisms in a Chinese Yi group

Study of InDel genetic markers with forensic and ancestry informative interest in PALOP’s immigrant populations in Lisboa

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