Genital basal cell carcinoma, a different pathogenesis from sun‐exposed basal cell carcinoma? A case‐control study of 30 cases

Abstract

HPV infection is mostly likely not involved in genital BCC pathogenesis. A greater level of p53 expression in genital BCCs implicates pathways other than ultraviolet (UV)-specific p53 mutations in their pathogenesis.

Metastatic basal cell carcinoma with atypical pattern of spread

“…BCC is most common in older patients, particularly men over the age of 60, and is increasing in incidence [1] . The vast majority (70%) of BCC present on the face, while less than 1% present in the genital region, likely due to lower exposure to sunlight and UV radiation [6] . The primary risk factor for BCC is a history of UV radiation exposure, although fair skin, arsenic exposure, radiation therapy, and immunosuppression also play a role [7] .…”

Cells to Surgery Quiz: April 2019

“…a. Pigmented basal cell carcinoma (BCC): Basal cell carcinoma (BCC) is a common skin cancer that occurs in adults, predominantly on the head and neck, followed by the trunk (Wang et al, 2018). Many subtypes of BCCs exist, including superficial, nodular, infiltrating, and pigmented types; approximately 7% of all BCCs are pigmented.…”

Nodular trichoblastoma or basal cell carcinoma: A diagnostic dilemma of clinical significance

“…9 Rare case reports of Basal cell carcinoma originating from non sun exposed areas have been reported in literature. 10 Histologically Basal cell carcinomas are composed of basaloid nests having connections with the overlying epidermis and may exhibit varying growth patterns including infiltrative, micronodular, morpheaform etc. The cells show nuclear hyperchromasia, frequent mitosis and apoptosis.…”