Genetische Ursachen der Adipositas

Giuranna, Johanna; Aschöwer, J.

doi:10.1007/s11377-016-0125-1

Cited by 2 publications

(6 citation statements)

References 28 publications

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“…Overall, 13 studies out of 18 studies reported data from nine different countries (mainly in Europe), on absenteeism in UC, capturing cost/loss of earning of absenteeism per patient year and/or total average indirect costs of absenteeism per patient year. With regards to presenteeism, we were only able to identify three studies, one conducted in Poland [14], one in Hungary [1] and one in Israel [2]. Four studies assessed total productivity loss, two in The Netherlands [15, 19], one in Serbia [22] and one in Poland [14].…”

Section: Resultsmentioning

confidence: 99%

“…With regards to presenteeism, we were only able to identify three studies, one conducted in Poland [14], one in Hungary [1] and one in Israel [2]. Four studies assessed total productivity loss, two in The Netherlands [15, 19], one in Serbia [22] and one in Poland [14]. Both presenteeism and productivity losses reported cost per patient year, in USD dollars converted to 2017 base year.…”

Section: Resultsmentioning

confidence: 99%

“…Three studies estimated indirect costs associated to presenteeism, one in Poland [14], one in Hungary [1] and one in Israel [2], as indicated in Table 5.…”

Section: Resultsmentioning

confidence: 99%

“…UC patients were poorly described in the publication by Kawalec et al [14] and in Katz Avitan et al [2], however, more information on patient characteristics was provided in Mandel et al [1]. In fact, it was reported that 11.5% of UC patients were on biologics and 8.3% of patients had underwent colectomy.…”

Section: Resultsmentioning

confidence: 99%

“…Total productivity losses were reported in four studies, one in Poland [14], one in Serbia [22] and two in the Netherlands [15, 19], as shown in Table 6. The proportion of indirect costs associated to total UC costs4 was reported in two studies, conducted in the Netherlands and by the same author.…”

Section: Resultsmentioning

confidence: 99%

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Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data

Constantin¹,

Atanasov²,

Wirth

et al. 2019

BMC Gastroenterol

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BackgroundThe economic burden of ulcerative colitis (UC), specifically related to indirect costs, is not extensively documented. Understanding and quantifying it is required by health care decision makers.AimTo assess the impact of indirect costs of UC in observation studies.MethodA systematic literature search was conducted in MEDLINE®, Embase® and Cochrane Library to capture all relevant publications reporting outcomes on absenteeism, presenteeism and productivity losses in moderate to severe UC. Eligibility criteria for inclusion into the review were established using a predefined PICOS scheme. All costs were adjusted to 2017 currency values (USD dollars, $).ResultsIn total, 18 studies reporting data on indirect costs were included in the analysis. Absenteeism costs were classified into three categories: sick leave, short-term and long-term disability. Most of the studies captured absenteeism costs related specifically to sick leave, which was experienced on average by 10 to 24% patients with UC. Only three studies captured presenteeism costs, as these are difficult to measure, however costs ranged from 1602 $ to 2947 $ per patient year. The proportion of indirect costs accounted for 35% of total UC costs (Total UC costs were defined as the sum of healthcare costs, productivity costs and out-of-pocket costs).DiscussionA limited number of studies were identified describing the indirect costs in patients with moderate to severe UC. Insufficient data on different components of costs allowed a limited analysis on the impact of indirect costs in patients with UC. Further studies are needed to gain an understanding of the influence of UC on patients’ functional abilities.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Three studies estimated indirect costs associated to presenteeism, one in Poland [14], one in Hungary [1] and one in Israel [2], as indicated in Table 5.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data

Constantin¹,

Atanasov²,

Wirth

et al. 2019

BMC Gastroenterol

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Quality of life and patient preferences among Danish patients with ulcerative colitis – results from a survey study

Hagelund¹,

Stallknecht²,

Jensen³

2020

Current Medical Research and Opinion

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Objective: To explore health-related quality of life (HRQoL) and assess preferences for medical treatment attributes to obtain information of the relative importance of the different attributes in a Danish population with ulcerative colitis (UC). Methods: We used data from an online survey collected in March 2018 among people with selfreported UC. A total of 302 eligible respondents answered the HRQoL questionnaires (EuroQol-5 Dimensions (EQ-5D-5L) and the Short Inflammatory Bowel Disease Questionnaire (SIBDQ)), and 212 also completed the discrete choice experiment (DCE). The probability of choosing an alternative from a number of choices in the DCE was estimated using a conditional logit model. Results: The respondents had an average SIBDQ score of 4.5 and an HRQoL score of 0.77, applying the EQ-5D-5L questionnaire. HRQoL correlated with disease severity, and the respondents had lower HRQoL than did a gender-and age-matched subset of the Danish population. The most important medical treatment attribute was efficacy within eight weeks. Additionally, respondents stated a preference for avoiding taking steroids, for fast onset of effect and for oral formulations. Conclusions: HRQoL correlates with disease severity, and patients with UC have lower HRQoL than the general population. The most important treatment attribute was efficacy, but patients also would like to avoid steroids, value fast onset of effect and prefer oral formulations. ARTICLE HISTORY

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Genetische Ursachen der Adipositas

Cited by 2 publications

References 28 publications

Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data

Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data

Quality of life and patient preferences among Danish patients with ulcerative colitis – results from a survey study

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