Genetics of fat tissue accumulation in pigs: a comparative approach

Świtoński, M.; Stachowiak, Monika; Cieślak, J.; Bartz, M.; Grzes, Maria

doi:10.1007/bf03195724

Cited by 95 publications

(70 citation statements)

References 124 publications

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“…The PRKAG3 AA animals also had less drip loss, which means higher water-holding capacity. Our results are consistent with previous reports in which the AA genotype pigs had Unfortunately, we did not have the backfat thickness records to test if the MC4R D298N polymorphism was associated with fat deposition traits in KNP x YS F2 animals, but it warrants the identification of the MC4R gene structure in KNP pigs to investigate the functional mechanisms of obesity-related phenotypes (Barb et al, 2010;Switonski et al, 2010). The CAST RsaI polymorphism was associated with moisture and crude protein levels (Table 4).…”

Section: Association Of Genotypes With the Phenotypessupporting

confidence: 91%

Development of Optimal Breeding Pigs Using DNA Marker Information

Kim¹,

Roh²,

Cho³

et al. 2010

Genomics & Informatics

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The aim of the study was to investigate pig reference families, generated from Korean native pigs (KNP) that were crossed with Yorkshire (YS) breeds, which were used to evaluate genetic markers to select breeding animals with superior pork quality. A set of five candidate genes (PRKAG3, MC4R, CAST, ESR, and PRLR ) was analyzed for association with pork quality traits. PRKAG3 (I199V) SNP genotypes were significantly associated with muscle moisture, protein, and fat contents.The MC4R D298N polymorphism was significantly associated with meat tenderness and color traits. The CAST polymorphism was significantly associated with muscle moisture and crude protein traits. These three genes have been associated with pork quality traits in other pig populations, and some of our results are consistent with earlier studies. In addition, two reproductive candidate genes (ESR and PRLR ) did not have significant associations. These results suggest that further study is warranted to investigate and develop more DNA markers associated with pork quality in our KNP-crossed pig families.

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Section: Association Of Genotypes With the Phenotypessupporting

confidence: 91%

Development of Optimal Breeding Pigs Using DNA Marker Information

Kim¹,

Roh²,

Cho³

et al. 2010

Genomics & Informatics

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“…Both IMF content and its fatty acid composition are considered to be quantitative traits, thus their phenotypic variability depends on genetic and environmental factors. The genetic background of porcine fatness traits has been studied extensively and to date a large number of candidate genes contributing to the phenotypic variability of these traits, as well as detection of QTL (quantitative trait locus), has been reported (Switonski et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

The fatty acid composition of the <i>Longissimus dorsi</i> muscle, subcutaneous and visceral fats differ in four commercial pig breeds

et al. 2012

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Fatness traits, including fatty acid (FA) composition, influence the dietary value of meat products. In this study we compared the fatty acid profiles in the carcasses of two main Polish breeds, Polish Large White (PLW) and Polish Landrace (PL), and two common commercial ones, Duroc and Pietrain. The Longissimus dorsi muscle, subcutaneous and visceral fats were sampled from 85 gilts that were fed the same diets and slaughtered at the same body weight (100 kg). Several significant between-breed differences were observed in FA composition, especially in subcutaneous and abdominal fat. In all tissues, the lowest percentage of saturated fatty acids (SFA) was observed in Pietrain pigs, with the differences depending mainly on C16:0 and C18:0. In abdominal fat, the highest content of monounsaturated fatty acids was found in that of PLW, chiefly due to an elevated content of C18:1 n-9. In both adipose tissues the highest content of polyunsaturated fatty acids (PUFA) was found in Pietrain and the lowest in PLW. These differences were mainly because of the high content of C18:2 in Pietrain pigs. The existence of between-breed and tissue differences was confirmed by linear discriminant analysis, which revealed that the studied tissues can be distinguished according to FA profile with an overall prediction ability of 89.8%. It was also shown that the percentage of PUFA in the studied tissues was negatively correlated with abdominal fat weight. We conclude that the FA profile in the carcass of Pietrain pigs is the most favourable, while two Polish breeds and the Duroc breed have similar FA profiles.

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“…In Polish native Złotnicka Spotted pigs, the meat with genotype hh was marked by a higher intramuscular fat content (2.64%) compared with the HH group (1.99%); P ≤0.05 (Hanna et al, 2010). Besides the H-FABP gene, 29 genes are associated with the IMF content (Switonski et al, 2010). There are two possible ways of improving IMF content: enhancing favourable alleles and crossbreeding.…”

Section: Discussionmentioning

confidence: 99%

Polymorphisms of candidate genes associated with meat quality and disease resistance in indigenous and exotic pig breeds of Vietnam

Cuong¹,

Thu²,

Thoa³

et al. 2012

SA J. An. Sci.

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The objectives of this study were to analyse genotype distribution and sequence variations of candidate genes putatively associated with meat quality and disease resistance in exotic and indigenous Vietnamese pig breeds. For this purpose, 340 pigs from four indigenous and two exotic breeds were included in the analysis of the polymorphisms of the heart fatty-acid-binding protein (H-FABP), alpha 1 fucosyltransferase (FUT1), and bactericidal/permeability-increasing protein (BPI) genes by the sequencing and PCR-RFLP methods. For H-FABP, 17 single nucleotide polymorphisms (SNPs) were detected in indigenous pig breeds by direct sequencing of a fragment at intron 2 of the H-FABP gene. The mutation T1556C created a new restriction site for the enzyme MspI, which gave rise to new allelic variants in three indigenous pig breeds. In indigenous breeds, the frequency of the favourable alleles a and d at MspI and HaeIII sites of the H-FABP gene were low. Meanwhile, the frequency of the d allele at the HaeIII site in exotic breeds was significantly higher than those of indigenous pig breeds. No mutation was found in the RFLP-fragment of the FUT1 gene of four indigenous pig breeds by sequencing, while in the BPI gene two mutations were detected in the Tap Na breed. The resistant alleles of the FUT1 and BPI genes in the exotic breeds were significantly higher than those of indigenous pig breeds. Among the indigenous pig breeds, the Tap Na breed possessed a higher frequency of the resistant allele G of BPI gene than the remaining breeds. The T1556C mutation at H-FABP may be important for the genetic improvement of intramuscular fat content and breed. Tap Na may be a source of resistant alleles for local ecologies.

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Genetics of fat tissue accumulation in pigs: a comparative approach

Cited by 95 publications

References 124 publications

Development of Optimal Breeding Pigs Using DNA Marker Information

Development of Optimal Breeding Pigs Using DNA Marker Information

The fatty acid composition of the <i>Longissimus dorsi</i> muscle, subcutaneous and visceral fats differ in four commercial pig breeds

Polymorphisms of candidate genes associated with meat quality and disease resistance in indigenous and exotic pig breeds of Vietnam

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