2010
DOI: 10.1007/bf03195724
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Genetics of fat tissue accumulation in pigs: a comparative approach

Abstract: Fatness traits are important in pig production since they influence meat quality and fattening efficiency. On the other hand, excessive fat accumulation in humans has become a serious health problem due to worldwide spread of obesity. Since the pig is also considered as an animal model for numerous human diseases, including obesity and metabolic syndrome, comparative genomic studies may bring new insights into genetics of fatness/obesity. Input of genetic factors into phenotypic variability of these traits is … Show more

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Cited by 95 publications
(72 citation statements)
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“…The PRKAG3 AA animals also had less drip loss, which means higher water-holding capacity. Our results are consistent with previous reports in which the AA genotype pigs had Unfortunately, we did not have the backfat thickness records to test if the MC4R D298N polymorphism was associated with fat deposition traits in KNP x YS F2 animals, but it warrants the identification of the MC4R gene structure in KNP pigs to investigate the functional mechanisms of obesity-related phenotypes (Barb et al, 2010;Switonski et al, 2010). The CAST RsaI polymorphism was associated with moisture and crude protein levels (Table 4).…”
Section: Association Of Genotypes With the Phenotypessupporting
confidence: 91%
“…The PRKAG3 AA animals also had less drip loss, which means higher water-holding capacity. Our results are consistent with previous reports in which the AA genotype pigs had Unfortunately, we did not have the backfat thickness records to test if the MC4R D298N polymorphism was associated with fat deposition traits in KNP x YS F2 animals, but it warrants the identification of the MC4R gene structure in KNP pigs to investigate the functional mechanisms of obesity-related phenotypes (Barb et al, 2010;Switonski et al, 2010). The CAST RsaI polymorphism was associated with moisture and crude protein levels (Table 4).…”
Section: Association Of Genotypes With the Phenotypessupporting
confidence: 91%
“…Both IMF content and its fatty acid composition are considered to be quantitative traits, thus their phenotypic variability depends on genetic and environmental factors. The genetic background of porcine fatness traits has been studied extensively and to date a large number of candidate genes contributing to the phenotypic variability of these traits, as well as detection of QTL (quantitative trait locus), has been reported (Switonski et al, 2010).…”
Section: Introductionmentioning
confidence: 99%
“…In Polish native Złotnicka Spotted pigs, the meat with genotype hh was marked by a higher intramuscular fat content (2.64%) compared with the HH group (1.99%); P ≤0.05 (Hanna et al, 2010). Besides the H-FABP gene, 29 genes are associated with the IMF content (Switonski et al, 2010). There are two possible ways of improving IMF content: enhancing favourable alleles and crossbreeding.…”
Section: Discussionmentioning
confidence: 99%