Genetic Variation and Covariation for Characteristics Associated with Cadmium Tolerance in Natural Populations of the Springtail Orchesella cincta (L.)

Posthuma, Leo; Hogervorst, R.F.; Joosse, Els N. G.; Straalen, Nico M. van

doi:10.2307/2410074

Cited by 65 publications

(43 citation statements)

References 31 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Genetic variation was indeed determined for EE, RGR and another characteristic associated with Cd tolerance, moulting frequency (Posthuma et al, 1993). The h 2 estimates for EE are comparable to those estimated for mt gene expression in the Roggebotzand population, and the question can be raised, does this imply that mt expression is mechanistically related to excretion efficiency?…”

Section: Discussionmentioning

confidence: 70%

“…Populations from mining sites were characterized by a higher cadmium (Cd) excretion efficiency and a lower Cd-induced growth reduction (Posthuma, 1990;Posthuma et al, 1992). To determine whether O. cincta can genetically adapt to heavy metals, additive genetic variation for Cd excretion efficiency was estimated by Posthuma et al (1993) in a reference population (originating from a clean soil). They showed a significant heritability (h 2 ) of 0.33 in a parentoffspring analysis and a significant h 2 of 0.48 in a half-sib analysis for this trait, implying that the reference population would be able to respond to selection resulting from heavy-metal exposure.…”

Section: Introductionmentioning

confidence: 99%

“…An experimental setup was chosen similar to Posthuma et al (1993) to perform parent-offspring regression experiments measuring genetic variation of the mt molecular phenotypes in a laboratory culture of the reference population Roggebotzand (The Netherlands). Families from a laboratory strain originating from the Roggebotzand population were either fed with noncontaminated food or with Cd amended food.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Additive genetic variation of transcriptional regulation: metallothionein expression in the soil insect Orchesella cincta

et al. 2005

View full text Add to dashboard Cite

Field-selected metal tolerance in Orchesella cincta is correlated with overexpression of the single copy cadmium (Cd) inducible metallothionein (mt). Previously, we have demonstrated large phenotypic variation in mt gene expression, and a higher frequency of high-expression phenotypes in a tolerant population. Here, we describe midparentoffspring regression analysis of mt gene expression in a laboratory culture originating from a noncontaminated natural population. Families were either not exposed (n ¼ 47) or exposed to 0.5 mmol Cd per gram dry food (n ¼ 46). Mean mt gene expressions normalized to 28S rRNA and b-actin RNA were generated using real-time RT-PCR applied to parents and offspring RNA and subjected to regression analysis. A significant heritability (h 2 ) for mt gene expression was estimated between 0.36 (b-actin normalized) and 0.46 (28S normalized) in Cd exposed families. Nontreated families did not yield a significant h 2 value. Restriction Fragment Length Polymorphism analysis of the metallothionein promoter sequence revealed eight promoter alleles that show structural variation. Three alleles show increased frequencies in families with high mt expression. Another gene, croquemort (isolated from a differential screening for 1 mmole Cd treatment) showed no h 2 of gene expression in response to 0.5 mmol Cd. This gene codes for a receptor-protein involved in recognition of apoptotic cells and may participate in the general stress response. The present data suggest that evolution of metal tolerance in O. cincta can occur in the field by selection for high mt expression due to structural changes in mt cis-regulation. Heredity (2006) 96, 85-92.

show abstract

Section: Discussionmentioning

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Additive genetic variation of transcriptional regulation: metallothionein expression in the soil insect Orchesella cincta

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Several taxon-specific mechanisms occur. Collembola, for instance, can accumulate metal in mid-gut epithelium and excrete this tissue periodically as part of the moult [729,730]. This epithelium contains granules, probably filled with calcium phosphate, which may be excreted into the gut lumen.…”

Section: One-compartment Kineticsmentioning

confidence: 99%

Dynamic Energy and Mass Budgets in Biological Systems

Kooijman

2000

793

1,202

View full text Add to dashboard Cite

second editionDynamic Energy Budget theory unifies the commonalities between organisms as prescribed by the implications of energetics, which link different levels of biological organization (cells, organisms and populations). The theory presents simple mechanistic rules that describe the uptake and use of energy and nutrients and the consequences for physiological organization throughout an organism's life cycle, including the relationships between energetics and aging and the effects of toxicants. In this new edition, the theory is broadened to encompass the fluxes of both energy and mass. All living organisms are now covered in a single quantitative framework, the predictions of which are tested against a wide variety of experimental results at the various levels of biological organization. The theory explains many general observations, such as the body size scaling relationships of certain physiological traits, and provides a theoretical basis for the widely used method of indirect calorimetry. In each case, the theory is developed in elementary mathematical terms, but a more detailed discussion of the methodological aspects of mathematical modelling is also included, making the book suitable for biologists and mathematicians with a broad interest in both fundamental and applied quantitative problems in biology.Bas Kooijman is Professor of Applied Theoretical Biology at the Vrije Universiteit in Amsterdam and is also head of the University's Department of Theoretical Biology. His research focuses on mathematical biology, in particular ecotoxicology which provided the framework for the original version of his Dynamic Energy Budget theory published in 1993 (Dynamic Energy Budgets in Biological Systems -Theory and Applications in Ecotoxicology). From the first edition:"This book is an excellent scientific product that informs and forces contemplation of issues relating to population and community ecology. The author has made a complex subject coherent." Thomas G. Hallam, Bulletin of Mathematical Biology "... a very useful and general tool to select more ecologically sound process equations and parameters in ecological models." Sven Erik Jørgensen, Ecological Modelling "The author has made a significant contribution to the problem of modelling the dynamics of biological populations at the level of the individual by synthesizing this very complicated subject into a relatively short list of general assumptions and putting the energetics of sub-models for vital rates on a solid basis." Jim Cushing, Mathematical Biosciences "The family of idealized models offered in this book is capable of playing a role analogous to that of Lotka-Volterra models in population dynamics ... I am confident that any model(s) capable of occupying this niche will be strongly influenced by the ideas in this book." Roger Nisbet, Ecology 9 LIVING TOGETHER Interaction between organisms: The spectrum from competition to preypredator systems. Evaluation of the consequences of the DEB model for population dynamics, food chains, and communities....

show abstract

“…The regulatory hubs that control these networks may be the key to explain adaptive phenotypes. Previous studies have provided evidence that whilst metal adapted populations matured earlier and juvenile body growth was faster, the adapted phenotype did not result in reduced fecundity (Posthuma et al 1992(Posthuma et al , 1993. Stress adaptation through transcriptional regulatory evolution has also been implicated in humans.…”

Section: Transcriptional Regulatory Evolution and Stress Tolerancementioning

confidence: 99%

The significance of genome-wide transcriptional regulation in the evolution of stress tolerance

Roelofs¹,

Morgan

Stürzenbaum

2010

Evol Ecol

View full text Add to dashboard Cite

It is widely recognized that stress plays an important role in directing the adaptive adjustment of an organism to changing environments. However, very little is known about the evolution of mechanisms that promote stress-induced variation. Adaptive transcriptional responses have been implicated in the evolution of tolerance to natural and anthropogenic stressors in the environment. Recent technological advances in transcriptomics provide a mechanistic understanding of biological pathways or processes involved in stress-induced phenotypic change. Furthermore, these studies are (semi) quantitative and provide insight into the reaction norms of identified target genes in response to specific stressors. We argue that plasticity in gene expression reaction norms may be important in the evolution of stress tolerance and adaptation to environmental stress. This review highlights the consequences of transcriptional plasticity of stress responses within a single generation and concludes that gene promoters containing a TATA box are more capable of rapid and variable responses than TATA-less genes. In addition, the consequences of plastic transcriptional responses to stress over multiple generations are discussed. Based on examples from the literature, we show that constitutive over expression of specific stress response genes results in stress adapted phenotypes. However, organisms with an innate capacity to buffer stress display plastic transcriptional responses. Finally, we call for an improved integration of the concept of phenotypic plasticity with studies that focus on the regulation of transcription.

show abstract

Genetic Variation and Covariation for Characteristics Associated with Cadmium Tolerance in Natural Populations of the Springtail Orchesella cincta (L.)

Cited by 65 publications

References 31 publications

Additive genetic variation of transcriptional regulation: metallothionein expression in the soil insect Orchesella cincta

Additive genetic variation of transcriptional regulation: metallothionein expression in the soil insect Orchesella cincta

Dynamic Energy and Mass Budgets in Biological Systems

The significance of genome-wide transcriptional regulation in the evolution of stress tolerance

Contact Info

Product

Resources

About