Genetic studies on temperature sensitive nonsense suppression

Gallucci, E.; Pacchetti, G.; Zangrossi, Sandro

doi:10.1007/bf00324053

Cited by 24 publications

(5 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mutation designated su-29 differs from the other suppressor mutations in that it is not effective at 42 "C. This is not unusual for nonsense suppressors. Similar cases were reported in studies on nonsense suppressors in yeast (RasseMessenguy & Fink, 1973) and Escherichia coli (Gallucci et al, 1970;Oescher & Woods, 1976). Moreover, in E. coli it was demonstrated that temperature sensitivity was the property of a mutant tRNA molecule (Abelson et al, 1970; Smith et al, 1970).…”

Section: J B a L A N D Otherssupporting

confidence: 78%

Allele Specific and Locus Non-specific Suppressors in Aspergillus nidulans

Bal

Kowalska

Maciejko

et al. 1979

Journal of General Microbiology

View full text Add to dashboard Cite

Using N-methyl-N'-nitro-N-nitrosoguanidine, ultraviolet irradiation, ethyl methanesulphonate or 4-nitroquinoline-1 -oxide mutagenesis and an enrichment method for the isolation of auxotrophs, 25 mutants with defects in the adA locus were obtained after screening 41 376 colonies. One of these, adA24, did not complement with any of the other adA mutants, had a very high reversion rate and had some other properties which usually characterize strains carrying nonsense mutations. All revertants of adA24 carried dominant suppressor mutations. A group of adA24 suppressors was tested for allele and locus specificity. They were found to suppress only some adA alleles, and at the same time, some mutations in the methG, methH, argB and proA loci. It is proposed that the allele specific and locus nonspecific adenine suppressors are suppressors of nonsense mutations.

show abstract

Section: J B a L A N D Otherssupporting

confidence: 78%

Allele Specific and Locus Non-specific Suppressors in Aspergillus nidulans

Bal

Kowalska

Maciejko

et al. 1979

Journal of General Microbiology

View full text Add to dashboard Cite

show abstract

“…A temperature-sensitive derivative of supC tRNA (Table 2) has also been described (72). All temperature-sensitive derivatives of supF and supC are devoid of suppressor activity at 42°C and have reduced activity at the permissive temperature (72,186). Three temperature-sensitive mutants with alterations in tRNAGIn (supE) ( Table 2) have also been reported (147).…”

Section: Temperature-sensitive Suppressionmentioning

confidence: 99%

Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli.

Eggertsson¹,

Söll²

1988

Microbiological Reviews

129

View full text Add to dashboard Cite

“…This would effectively make all nonsense mutations available for temperature shift studies, and the sensitive step would be at the point of synthesis. Such mutants are known in other species (27,98,236,279), and should be obtainable in B. subtilis.…”

Section: Temperature-sensitive Mutantsmentioning

confidence: 99%

Genetic aspects of bacterial endospore formation.

Piggot¹,

Coote²

1976

Bacteriological Reviews

405

283

View full text Add to dashboard Cite

95 cysA14 60 ery-1 25 purA 49 metC3; 21 ura-1 c 42 ura-26 s 83 ura-1; 5 metC3 ' 54 lys-l' 44 trpC2 35 trpC2 33 Iys-1; 16 trpC2 56 lys-1 25 phe-1; 10 ilvCl RI = 0.1 12 hisAI RI s 0.2 47 ura-1; 1 metC3 12 ura-26 16 ura-1; 49 metC3 49 52 148 307 24 phe-12; 1 lys-l 49 B 49 49, 143, 334 49 244 49 a Linkage with vegetative markers is expressed as % cotransfer. Linkage between spo mutations is expressed as the recombination index (RI [170]). b A, J.A. Hoch, personal communication; B, M. Young, personal communication; C, P.J. Piggot, unpublished observations. I Assignment to locus is not certain, see text. d If 94U (reference 148) is the same as 94 (reference 257), then this has the same phenotype as spoIVC mutants described by Coote (49, 50), and the mutations should be placed in the spoIVC locus.

show abstract

Genetic studies on temperature sensitive nonsense suppression

Cited by 24 publications

References 22 publications

Allele Specific and Locus Non-specific Suppressors in Aspergillus nidulans

Allele Specific and Locus Non-specific Suppressors in Aspergillus nidulans

Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli.

Genetic aspects of bacterial endospore formation.

Contact Info

Product

Resources

About