Genetic polymorphisms in IL-1A and IL-1B isoforms and their associations with chronic periodontitis in the Swahili people of Kenya

Wagaiyu, Evelyn; Bulimo, Wallace; Wanzala, Peter; T, Kaimenyi Jacob

doi:10.9790/0853-131120715

IOSRJDMS

2014

DOI: 10.9790/0853-131120715

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Genetic polymorphisms in IL-1A and IL-1B isoforms and their associations with chronic periodontitis in the Swahili people of Kenya

Evelyn Wagaiyu¹,

Wallace Bulimo²,

Peter Wanzala³

et al.

Abstract: Genetic polymorphisms in interleukin-1 (IL-1A and IL-1B) isoforms have been associated withChronic Periodontitis (CP) (OR = 3.16, p<0.001). Allele 1 at locus (OR=5.2, p=0.005), moderate (OR=4.51, p<0.001) and severe disease (OR=2.19, p=0.042

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Genetic polymorphisms in IL-1A and IL-1B isoforms and their associations with chronic periodontitis in the Swahili people of Kenya

Abstract: Genetic polymorphisms in interleukin-1 (IL-1A and IL-1B) isoforms have been associated withChronic Periodontitis (CP) (OR = 3.16, p<0.001). Allele 1 at locus (OR=5.2, p=0.005), moderate (OR=4.51, p<0.001) and severe disease (OR=2.19, p=0.042

Cited by 2 publications

References 35 publications

Antagonistic effect of IL1 variants in periodontitis and external apical root resorption: Evidence from a literature review

Antagonistic effect of IL1 variants in periodontitis and external apical root resorption: Evidence from a literature review

Association between the rs1143634 polymorphism in interleukin-1B and chronic periodontitis: Results from a meta-analysis composed by 54 case/control studies

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