Genetic Differences in the Time of Appearance of Cellular Antigens in the Chicken

Genetic Differences in the Homologous Splenomegaly Reaction in Chickens Due to the Donor

“…There were no alleles common to these breeds. The serological methods and the nomenclature used in the present studies had been previously presented by Matsumoto and Okada (1961) and Okada, Takagi and Matsumoto (1962). The relationship of the alleles shown in the present paper (BA, BC, BG, BI) to those of Briles et al (1950Briles et al ( , 1957) (B', B2, B3, ...) is still obscure, though the comparison tests between them are under way (Okada, McDermid and Hachinohe 1969).…”

Developmental Changes in Some Blood Group Antigens in the Chick

“…The Q antigen showed the similar curve to the B antigen of the B system with respect to the hemagglutination activity. Changes in percentages of immature (round shape) and mature (oval shape) red cells in the blood of embryos at various stages of development indicate that the immature red cells showed a high level in blood of 3-day embryos, and decreased gradually as the developmental stages progress, but the mature red cells showed a low level at third day Briles et al (1948) and Okada et al (1962) that antigens of the A system were fully expressed in the early stage of embryos, and antigens of the B system appeared to develop slowly and often were not expressed during the embryonic stages but apparently appeared after hatching. In the present investigation, it was confirmed that the antigens of the A system were fully expressed in the early embryonic stage as reported previously, but with antigens of other systems different results were observed.…”

“…Ino (1950) found that the agglutinability of red cells in the Rh and Q systems was highest in fetuses immediately before birth and decreased acutely after birth. Briles et al (1948) and Okada et al (1962) reported that some antigens of the B system appeared at the fifth-sixth day after hatching. Okada et al (1962) determined the time of appearance from the comparison between the expected values from the genotypes of parantal populations and observed number of birds giving positive reaction.…”

“…Briles et al (1948) and Okada et al (1962) reported that some antigens of the B system appeared at the fifth-sixth day after hatching. Okada et al (1962) determined the time of appearance from the comparison between the expected values from the genotypes of parantal populations and observed number of birds giving positive reaction. Mikami et al (1969) found that the splenomegaly was induced in B'B' embryos by injection with the blood of BABA and BCBC adults when the blood from the latter was injected intravenously into 14-day embryos of the former, the spleen of which was weighed at 5th day after injection.…”

“…In the B system only one antigen was found as early as the third day of incubation, and other three antigens were first detectable on the sixth day after hatching. Okada et al (1962) detected eleven antigens belonging to three systems, B, F and H, in the development of chickens (later, the F and H systems were combined into one system which was redesignated as A system, Okada, personal communication). Two antigens in the A system were detected at the early embryonic stages, but in the B system A, B, C, and G antigens were detected in 11-day embryos, K, L, and M antigens (the last controlled by the allele BBM) were detectable in 14-day embryos, and I and M antigens (the last controlled by the gene BM) first appeared on the fifth day after hatching.…”