Genetic Differences among Chicken Embryos in Response to Inoculation with an Isolate of Infectious Bronchitis Virus

Purchase, H. G.; Ch, Cunningham; Br, Burmester

doi:10.2307/1588346

Cited by 14 publications

(6 citation statements)

References 11 publications

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“…This also confirmed in the current study where IBV titers declined sharply at 120 h PI. It is well known that maximum IBV virus titers reached 1 to 2 days post-inoculation [ 16 - 18 ] but interestingly, allantoic fluid showed high virus titers 24–87 h PI. Immunostaining of the CAM was positive in all inoculated eggs from which infectious virus was recovered.…”

Section: Discussionmentioning

confidence: 99%

Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos

et al. 2009

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Background: Infectious bronchitis virus primarily induces a disease of the respiratory system, different IBV strains may show variable tissue tropisms and also affect the oviduct and the kidneys. Proventriculitis was also associated with some new IBV strains. Aim of this study was to investigate by immunohistochemistry (IHC) the tissue tropism of avian infectious bronchitis virus (IBV) strain M41 in experimentally infected chicken embryos.

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Section: Discussionmentioning

confidence: 99%

Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos

et al. 2009

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“…Mac-Donald et al (1980) described fewer pathological changes in kidneys of chickens infected at 3 weeks of age than those infected at day-old or 10 weeks of age, although the virus was inoculated i.v., which is an unnatural route of infection. Purchase et al (1966) demonstrated variation in mortality following IBV inoculation of embryos from different inbred lines. Bumstead et al (1989) compared mortalities in several inbred lines of chickens following inoculation with a pool of strains of IBV and/or Escherichia coli and found marked differences among them.…”

Section: Agementioning

confidence: 98%

Infectious bronchitis virus: Immunopathogenesis of infection in the chicken

1997

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SUMMARYThe immunopathogenesis of infectious bronchitis virus (IBV) infection in the chicken is reviewed. While infectious bronchitis (IB) is considered primarily a disease of the respiratory system, different IBV strains may show variable tissue tropisms and also affect the oviduct and the kidneys, with serious consequences. Some strains replicate in the intestine but apparently without pathological changes. Pectoral myopathy has been associated with an important recent variant. Several factors can influence the course of infection with IBV, including the age, breed and nutrition of the chicken, the environment and intercurrent infection with other infectious agents. Immunogenic components of the virus include the S (spike) proteins and the N nucleoprotein. The humoral, local and cellular responses of the chicken to IBV are reviewed, together with genetic resistance of the chicken. In long-term persistence of IBV, the caecal tonsil or kidney have been proposed as the sites of persistence. Antigenic variation among IBV strains is related to relatively small differences in amino acid sequences in the S1 spike protein. However, antigenic studies alone do not adequately define immunological relationships between strains and cross-immunisation studies have been used to classify IBV isolates into 'protectotypes'. It has been speculated that changes in the S1 protein may be related to differences in tissue tropisms shown by different strains. Perhaps in the future, new strains of IBV may arise which affect organs or systems not normally associated with IB.

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“…Differences in susceptibility for IBV between chicken lines can also have an effect on different assays or detection methods. Purchase et al (1966) Housing of the chicken. In principle, the period for which IBV can be detected in a group of chickens could be prolonged when the virus circulates between birds (Cook, 1968).…”

Section: Level Of Immunity In the Chicken At The Moment Of Infectionmentioning

confidence: 99%

“…IBV grows well in the developing chicken embryo, the maximum virus titre in allantoic fluid is reached 1 to 2 days post-inoculation (Hitchner & White, 1955;Purchase et al, 1966;Clarke et al, 1972;Darbyshire et al, 1975), although this peak can be delayed for non-egg-adapted field strains. For isolation of non-egg-adapted field strains (a "field" strain could also be a re-isolation of vaccine), several sequential passages can be given to increase the amount of virus before performing the antigen detection method.…”

Section: Virus Isolation (Multiplication and Detection Of Infectious mentioning

confidence: 99%

Detection of infectious bronchitis virus

Wit¹

2000

Avian Pathology

166

128

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The detection methods for infectious bronchitis virus (IBV) are reviewed. Advantages and disadvantages of available techniques of IBV detection by virus isolation, antigen or genome detection, and serology are discussed. Factors of influence on the level of success in detection of IBV after a disease outbreak are discussed, as are the possibilities and dangers of strain classification by protectotyping, serotyping, epitope-typing and genotyping.

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Genetic Differences among Chicken Embryos in Response to Inoculation with an Isolate of Infectious Bronchitis Virus

Cited by 14 publications

References 11 publications

Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos

Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryos

Infectious bronchitis virus: Immunopathogenesis of infection in the chicken

Detection of infectious bronchitis virus

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