Abstract:Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a common condition affecting approximately 0.3-4 % of the middle-aged population. A hereditary component to the condition has long been identified but the genetic basis has been difficult to elucidate. Not least of the difficulties resides in a single definition of the phenotype. In an attempt to unravel some of the components, which might contribute to the expression of the syndrome, 'intermediate phenotypes' such as craniofacial structure, obesity, and u… Show more
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