Genes and phenotypes in the Samaritan isolate

Bonné, Batsheva

doi:10.1002/ajpa.1330240102

Cited by 33 publications

(13 citation statements)

References 19 publications

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“…The picture is typical of the Arabs with very little Afri can admixture as evidenced by very low Tf" gene. Similar frequencies of Hp have been reported for Arabs in Israel [2], in Baghdad |4| and Lebanon |! 1|.…”

Section: Serum Proteinssupporting

confidence: 82%

A Genetic Study of the Jordanians

Banerjee¹,

Saha²,

Daoud³

et al. 1981

Hum Hered

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A total of 543 random samples of blood collected from unrelated male blood donors of Amman, Jordan, were analysed for ABO and Rh(D) blood groups, serum haptoglobin, transferrin and albumin; glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, lactate dehydrogenase; and haemoglobin phenotypes. The results of the study establish the Arab characteristics of the population with no or minimal presence of African genes.

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Section: Serum Proteinssupporting

confidence: 82%

A Genetic Study of the Jordanians

Banerjee¹,

Saha²,

Daoud³

et al. 1981

Hum Hered

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“…An interesting finding is the fact that a higher percentage of males exhibit the lighter eye colors (x2 = 14.94; p < 0.001). A similar phenomenon was observed among the Samaritans [5].…”

Section: Anthropological Observationssupporting

confidence: 82%

“…On the other hand, as would be expected, they show marked differences in all measurements from various other Jewish communities such as the lraqui [11] or Moroccans or from isolated smaller groups as the Mzab or the Samaritans [5].…”

Section: A Means and Indices O F Metrical Characteristicssupporting

confidence: 52%

The Habbanite Isolate. III.

Bonné¹,

Ashbel²,

Berlin³

et al. 1972

Hum Hered

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A morphological characterization of the Habbanite community in Israel included about 25 anthropometric measurements and some 10 observations for 239 males and 267 females. The Habbanites can be described as rather short in stature, hyperbrachycephalic with long but narrow facial features. Heights and weights estimates of 275 Habbanite boys and girls, 6–17 years of age, are much lower than those of British or US children (below the 3rd percentile), and also lower than those of children from various other ethnic groups in Israel. The coefficient of variations for metric characteristics is not different between the sexes. Uniformity of type is also reflected in traits such as hair and eye color. Determination of taste thresholds for phenylthiocarbamide (PTC) indicates solutions No. 9 and 10 as the mode for tasters. The percentage of non-tasters is not very low (19.75%). Only two males had defects in color vision; both their mothers were not from Habban. The Habbanites’ physical features do not resemble those of the populations surrounding them or among whom they have been dwelling for several hundred years. It is claimed that on the basis of these results, together with the serological and dermatoglyphic data, the Habbanites can be regarded as a true genetic isolate.

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“…Population isolates have long been a subject of interest for population geneticists [1, 2, 3, 4, 5, 6, 7, 8]and medical geneticists [9, 10, 11]. Recently, there has been a resurgence of interest in these populations on two fronts.…”

Section: Introductionmentioning

confidence: 99%

Gene Mapping in Isolated Populations: New Roles for Old Friends?

et al. 1999

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Population isolates are increasingly being used in attempts to map genes underlying complex diseases. To further explore the utility of isolates for this purpose, we explore linkage disequilibrium patterns in polymorphisms from two regions (VWF and NF1) in three isolated populations from Finland. At the NF1 locus, the Finnish populations have greater pairwise disequilibrium than populations from Africa, Asia, or northern Europe. However, populations from ‘New Finland’ and ‘Old Finland’ do not differ in their disequilibrium levels at either the NF1 or the VWF locus. In addition, disequilibrium patterns and haplotype diversity do not differ between a sample from the Åland Islands, Finland, and a collection of outbred Centre d’Etude du Polymorphisme Humain families. These results show that linkage disequilibrium patterns sometimes differ among populations with different histories and founding dates, but some putative isolated populations may not significantly differ from larger admixed populations. We discuss factors that should be considered when using isolated populations in gene-mapping studies.

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Genes and phenotypes in the Samaritan isolate

Cited by 33 publications

References 19 publications

A Genetic Study of the Jordanians

A Genetic Study of the Jordanians

The Habbanite Isolate. III.

Gene Mapping in Isolated Populations: New Roles for Old Friends?

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