The problem of the retrofit design of a multiproduct batch plant is considered from a new
perspective that involves explicit consideration of inherent reliability and maintainability
characteristics of existing and new equipment. Until now, in multiproduct batch plant retrofitting
formulations, the production capacity has been specified by the limiting batch size and limiting
cycle time. We propose a more robust retrofit solution that is obtained by defining the effective
production capacity by three parameters: the limiting batch size, the limiting cycle time, and
the overall plant availability. The novel simultaneous optimization framework developed in this
work combines a process model and an availability model to obtain the optimal size, optimal
operating mode, and optimal allocation of inherent availability for new equipment during the
retrofit stage. The overall problem is formulated as a mixed integer nonlinear programming
(MINLP) model, and its applicability is demonstrated through the solution of a number of
examples. This framework provides the designer with the opportunity to select the initial inherent
availability of new equipment during retrofitting by balancing the costs of design investments
against the costs of downtime.