“…Post-operative pain as measured by the VAS score was in favor of group (S) throughout the post-operative period (1, 2, 4, 12 h) with pvalue= <0.001, while Gurudatta and Arif 's study [10], and Bessa et al study found that the difference was non-significant after 6 h 8 but Imbelloni et al showed significant difference at 2, 4, 6 h but nonsignificant difference at 12 h in his study comparing general and spinal anesthesia in laparoscopic cholecystectomy [13].…”