“…For example fibronectin 1, which in our study was significantly upregulated in fibroids with four independent probe sets, has been reported as downregulated in fibroids in a microarray study containing only six fibroid samples (Chegini et al, 2003). The changes in the expression profiles observed between normal myometrium and fibroid tissue also confirmed some previously reported results (Kovacs et al, 2001;Tsibris et al, 2002;Ahn et al, 2003;Chegini et al, 2003;Wang et al, 2003;Weston et al, 2003). For example, CCND1, endothelin receptor type A (EDNRA), collagen type III alpha 1 (COL3A1), and collagen type IV alpha 2 (COL4A2) were upregulated, and early growth response 1 (EGR1), complement component 1r (C1R), actin binding LIM protein 1 (ABLIM1), v-jun sarcoma virus 17 oncogene homolog (JUN), and B-cell CLL/lymphoma 6 (BCL6) were downregulated in fibroids.…”