Gene expression in the cardiovascular system of the domestic sheep (Ovis aries); a new tool to advance our understanding of cardiovascular disease

Abstract

24 25 Large animal models are of increasing importance in cardiovascular disease research as they 26 demonstrate more similar cardiovascular features (in terms of anatomy, physiology and size) to 27 provides a foundation to explore the transcriptome of the developing cardiovascular system and is a 46 valuable resource for the fields of mammalian genomics and cardiovascular research. 47 48 49 50 51

Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries)

“…The authors are also grateful for the support of the FAANG Data Coordination Centre (http: //data.faang.org) in the upload and archiving of the sample data and metadata and BioGPS (http://biogps.org) for hosting the sheep atlas dataset on their annotation portal. An early version of this manuscript was available as a preprint on BioRxiv (Tsang et al, 2020).…”