Gene expression analysis of inflammation-related genes in macrophages treated with α-(1 → 3, 1 → 6)-D-glucan extracted from Streptococcus mutans

Han, Kook-Il; Jung, Eui‐Man; Kwon, Hyun-Jung; Patnaik, Bharat Bhusan; Baliarsingh, Snigdha; Kim, Wan-Jong; Nam, Kwanghee; Lee, Jung-Sook; Han, Man-Deuk; Kang, Se Won

doi:10.1016/j.ijbiomac.2020.10.054

Cited by 6 publications

(3 citation statements)

References 23 publications

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“…Although the spoilage of bakery products is mainly due to moulds, the roping of the bread, caused by Bacillus sp., especially B. subtilis, is also a very large economical challenge [122,123]. Extracts of U. intestinalis showed inhibitory properties against S. mutans, an anaerobic gram-positive bacterium [124], which causes dental caries [125]. S. mutans secretes glycosyltransferases, which synthesize intracellular and extracellular polysaccharides [126].…”

Section: Antimicrobial Activity Of the Algal Extract Samplesmentioning

confidence: 99%

Characterization of Macro- and Microalgae Extracts Bioactive Compounds and Micro- and Macroelements Transition from Algae to Extract

Tolpežnikaitė

Bartkevičs

Ružauskas

et al. 2021

Foods

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The aim of this study was to evaluate the characteristics of macroalgae (Cladophora rupestris, Furcellaria lumbricalis, Ulva intestinalis) and microalgae (Arthrospira platensis (Sp1, Sp2), Chlorella vulgaris) extracts, including micro- and macroelement transition to extract, antioxidant, antimicrobial properties, the concentrations of chlorophyll (-a, -b), and the total carotenoid concentration (TCC). In macroalgae, the highest TCC and chlorophyll content were found in C. rupestris. In microalgae, the TCC was 10.1-times higher in C. vulgaris than in Sp1, Sp2; however, the chlorophyll contents in C. vulgaris samples were lower. A moderate negative correlation was found between the chlorophyll-a and TCC contents (r = −0.4644). In macroalgae extract samples, C. rupestris and F. lumbricalis showed the highest total phenolic compound content (TPCC). DPPH antioxidant activity and TPCC in microalgae was related to the TCC (r = 0.6191, r = 0.6439, respectively). Sp2 extracts inhibited Staphylococcus haemolyticus; C. rupestris, F. lumbricalis, U. intestinalis, and Sp2 extracts inhibited Bacillus subtilis; and U. intestinalis extracts inhibited Streptococcus mutans strains. This study showed that extraction is a suitable technology for toxic metal decontamination in algae; however, some of the desirable microelements are reduced during the extraction, and only the final products, could be applied in food, feed, and others.

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Section: Antimicrobial Activity Of the Algal Extract Samplesmentioning

confidence: 99%

Characterization of Macro- and Microalgae Extracts Bioactive Compounds and Micro- and Macroelements Transition from Algae to Extract

Tolpežnikaitė

Bartkevičs

Ružauskas

et al. 2021

Foods

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“…Dental caries is one of the most common oral diseases worldwide and has been associated with various disorders [ 1 , 2 ]. Environmental factors, including diet, oral bacteria, oral hygiene, and oral quality of life, contribute to the development of oral diseases including dental caries and periodontal diseases, leading to plaque biofilm formation on the tooth surface [ 1 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Among several distinct oral pathogenic bacteria, Streptococcus mutans , an anaerobic, gram-positive bacteria, is a major contributor to dental caries [ 1 , 2 , 4 ]. One study indicated that S. mutans secretes glycosyltransferases (GTFs), which play a critical role in biofilm formation on the tooth [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Probiotic Lactobacillus plantarum Ln4 Showing Antimicrobial and Antibiofilm Effect against Streptococcus mutans KCTC 5124 Causing Dental Caries

Jang,

Kim,

Lee

et al. 2023

J. Microbiol. Biotechnol.

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Dental caries has known as an infectious disease that is considered a serious global public health problem. Recently, report indicate that probiotics play a vital role in maintaining oral health. Therefore, this study aimed to evaluate the prevention effects of Lactobacillus plantarum Ln4 against dental infection by the pathogenic bacterium Streptococcus mutans KCTC 5124 through biofilm formation inhibition. To evaluate such prevention effects against S. mutans KCTC 5124, antimicrobial activity, auto-aggregation, co-aggregation, cell surface hydrophobicity, total exopolysaccharide (EPS) production rate, and biofilm formation were analyzed. Results showed that L. plantarum Ln4 showed higher antimicrobial activity than L. rhamnosus GG (LGG). In the group treated with L. plantarum Ln4, the co-aggregation (58.85%), cell surface hydrophobicity (16.75%), and EPS production rate (73.29%) values were lower than those of LGG and the negative control. Additionally, crystal violet staining and confocal laser scanning microscopy (CLSM) revealed that L. plantarum Ln4 effectively inhibited biofilm formation in S. mutans KCTC 5124. Therefore, L. plantarum Ln4 could be used in the industry as a probiotics to prevent and improve oral health.

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α-D-1,6-glucan from Castanea mollissima Blume alleviates dextran sulfate sodium-induced colitis in vivo

Cao

Xie

et al. 2022

Carbohydrate Polymers

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Gene expression analysis of inflammation-related genes in macrophages treated with α-(1 → 3, 1 → 6)-D-glucan extracted from Streptococcus mutans

Cited by 6 publications

References 23 publications

Characterization of Macro- and Microalgae Extracts Bioactive Compounds and Micro- and Macroelements Transition from Algae to Extract

Characterization of Macro- and Microalgae Extracts Bioactive Compounds and Micro- and Macroelements Transition from Algae to Extract

Probiotic Lactobacillus plantarum Ln4 Showing Antimicrobial and Antibiofilm Effect against Streptococcus mutans KCTC 5124 Causing Dental Caries

α-D-1,6-glucan from Castanea mollissima Blume alleviates dextran sulfate sodium-induced colitis in vivo

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