Gender differences in airway behaviour over the human life span

Sex-specific effect of IL9 polymorphisms on lung function and polysensitization

“…3 It is of interest to note that in this study, the IL9 polymorphism was associated both to lung function (FEV 1 /H 2 ) and to a marker of polysensitization. Sex differences in asthma-related traits may depend on genetic factors, but also on environmental factors and hormonal factors, and more likely on the complex interactions between these factors.…”

“…2 Asthma prevalence is higher in boys than in girls in childhood but this reverses around puberty, with higher prevalence in adult women than in men, and it is again higher in men than in women after menopause. 3 Asthma and atopy-related phenotypes also show sexual dimorphism in humans. These sex differences may result from many factors including genetic, developmental, immunological, hormonal, cultural and environmental factors, but little is known about the actual role of these factors.…”

“…These sex differences may result from many factors including genetic, developmental, immunological, hormonal, cultural and environmental factors, but little is known about the actual role of these factors. 3,4 Despite the numerous genetic studies conducted to date to identify the genetic determinants of asthma and asthma-related phenotypes, 5 only a few of them have been stratified by sex. Sex-specific effects of a few candidate genes associated with asthma and atopy phenotypes have been reported recently.…”

Geriatric dyspnea: Doing worse, feeling better

“…In addition, differential effects of ageing on dyspnea in men and women will be an important topic for future research. For instance, there are protective hormonal effects in woman that reduced age effects on the physiology of the respiratory system until menopause (Becklake & Kauffmann, 1999;Behan et al, 2002;Ofir et al, 2008). …”

Proposición de nuevas ecuaciones para calcular valores espirométricos de referencia en población chilena adulta: Sociedad Chilena de Enfermedades Respiratorias (SER)

“…Su interpretación requiere de valores de referencia para su comparación con mediciones realizadas en un sujeto 6 . Numerosos factores influyen en los valores de función pulmonar 7 , los más importantes son el sexo 8 , la edad, la antropometría 9 , la etnia 10 y el tabaquismo 11 . Se han demostrado valores significativamente mayores en poblaciones residentes en altura geográfica 12,13 .…”